{"id":"W2054176143","doi":"10.1016/j.neuroimage.2013.04.048","title":"Mapping the effects of ApoE4, age and cognitive status on 18F-florbetapir PET measured regional cortical patterns of beta-amyloid density and growth","year":2013,"lang":"en","type":"article","venue":"NeuroImage","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Avid Radiopharmaceuticals; National Institute on Aging; National Institutes of Health; Alzheimer's Disease Neuroimaging Initiative","keywords":"Alzheimer's disease; Apolipoprotein E; Senile plaques; Temporal lobe; Amyloid (mycology); Medicine; Internal medicine; BETA (programming language); Pathology; Neuroscience; Psychology; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001218246,0.0006225153,0.0003564899,0.0007265727,0.0001864322,0.0006363668,0.000292225,0.0003689368,0.001356929],"category_scores_gemma":[0.001822458,0.0003822591,0.000381267,0.0004054163,0.0004030564,0.0004910942,0.0001722071,0.0002707374,0.000194455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002691074,"about_ca_system_score_gemma":0.0002572734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003077262,"about_ca_topic_score_gemma":0.005632238,"domain_scores_codex":[0.9997161,0.0001053395,0.00002397127,0.00006430259,0.00004302001,0.00004720059],"domain_scores_gemma":[0.999042,0.0005370071,0.0001869094,0.00007820284,0.00008524656,0.00007063556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.04604173,0.0008995252,0.576679,0.0001456661,0.0009952716,0.001277203,0.0009086048,0.0008745633,0.34222,0.0002014418,0.0001687067,0.02958824],"study_design_scores_gemma":[0.00006330632,0.00212831,0.9683267,0.000005223608,0.0002775738,0.0009346543,0.0001705926,0.001084695,0.02662426,0.0001848151,0.0001836298,0.00001616274],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993438,0.0001552786,0.0002201824,0.000005755275,0.000001832814,0.000004320613,0.00005434902,0.000004713077,0.000209777],"genre_scores_gemma":[0.9988827,0.00007668016,0.000364903,0.00001072607,0.000002371024,0.000008813312,0.00006250853,0.000009887674,0.0005814809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003077262,"threshold_uncertainty_score":0.006442785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03350195642129561,"score_gpt":0.2800571145417014,"score_spread":0.2465551581204058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}