{"id":"W2054235839","doi":"10.1006/abbi.2000.2143","title":"FADD Null Mouse Embryonic Fibroblasts Undergo Apoptosis after Photosensitization with the Silicon Phthalocyanine Pc 4","year":2001,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Amgen (Canada); University of Toronto; Ontario Institute for Cancer Research","funders":"U.S. Public Health Service; National Cancer Institute; U.S. Food and Drug Administration","keywords":"FADD; Ceramide; Apoptosis; Tumor necrosis factor alpha; Cell biology; Programmed cell death; Chemistry; Ceramide synthase; Cancer research; Biology; Molecular biology; Caspase; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004421983,0.0001999265,0.0001636173,0.00001908061,0.00009396345,0.00002567753,0.0001418187,0.00007874622,0.000005919475],"category_scores_gemma":[0.00001369653,0.000141634,0.00008151006,0.0001053216,0.000293129,0.000006947987,0.00009862577,0.00008914953,9.592567e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002417311,"about_ca_system_score_gemma":0.00004026356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001100181,"about_ca_topic_score_gemma":0.000003565905,"domain_scores_codex":[0.9991779,0.00002930195,0.0001398355,0.0003282429,0.0001130484,0.000211667],"domain_scores_gemma":[0.9994158,0.00003160791,0.0001085031,0.0003371183,0.00003736034,0.00006959553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000438014,0.00005999045,0.0004689796,0.00006334005,0.00006999472,0.0000014926,0.0001107452,0.00005590258,0.9974481,0.00002617074,0.00005328031,0.001204011],"study_design_scores_gemma":[0.000519629,0.0001339302,0.000635531,0.00004084076,0.00004683741,0.00001963616,0.0001979819,0.0001245959,0.9974231,0.00005531407,0.0006060231,0.0001966461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976727,0.0005091191,0.0008507172,0.0001635138,0.0000210103,0.0001069357,0.0000359155,0.00001099377,0.0006291178],"genre_scores_gemma":[0.9979659,0.0004753712,0.0002603231,0.0001481199,0.0002635578,0.00001269027,0.0001396372,0.0000213182,0.0007131001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001007365,"threshold_uncertainty_score":0.5775669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003892374387579137,"score_gpt":0.1912190690680929,"score_spread":0.1873266946805137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}