{"id":"W2054295839","doi":"10.1016/j.cellsig.2005.05.004","title":"RGS2 interacts with Gs and adenylyl cyclase in living cells","year":2005,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; McGill University; Montreal Heart Institute; Western University","funders":"","keywords":"RGS2; Adenylyl cyclase; Heterotrimeric G protein; Gs alpha subunit; G protein; HEK 293 cells; Green fluorescent protein; Cell biology; Molecular biology; Luciferase; Signal transduction; Chemistry; Biology; Transfection; Receptor; GTPase-activating protein; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002634965,0.000183102,0.0001608403,0.00006990964,0.00006698926,0.00006226917,0.0001224039,0.0001230382,0.0001245007],"category_scores_gemma":[0.00001966942,0.0001672852,0.00004411442,0.00007392695,0.0000322331,0.00001135832,0.00007546748,0.0001557219,0.00001252437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000165195,"about_ca_system_score_gemma":0.00003216113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001640494,"about_ca_topic_score_gemma":0.00004725364,"domain_scores_codex":[0.9989345,0.00005034922,0.0002167485,0.0003877588,0.0001179933,0.0002926333],"domain_scores_gemma":[0.9995999,0.00002921044,0.00007035217,0.0001589925,0.00003486963,0.0001066835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003111413,0.00003914764,0.0003650869,0.00001805163,0.00001694985,0.00001816137,0.0002431791,0.002960293,0.9942036,0.00003299924,0.00002641923,0.002045013],"study_design_scores_gemma":[0.0003130089,0.000148747,0.00003638073,0.0001564665,0.00001175929,0.00001128411,0.0001892445,0.003032946,0.9927707,0.00001598946,0.003067855,0.0002455726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9706594,0.001892652,0.0268273,0.00003686911,0.00006544757,0.000126886,0.000001514458,0.00001265545,0.0003772335],"genre_scores_gemma":[0.9939005,0.0001549955,0.005037906,0.0001556351,0.0002931216,0.000009422928,0.00001529741,0.00003534479,0.0003977254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02324111,"threshold_uncertainty_score":0.6821691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00497292064144097,"score_gpt":0.1929155418559729,"score_spread":0.1879426212145319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}