{"id":"W2054295839","doi":"10.1016/j.cellsig.2005.05.004","title":"RGS2 interacts with Gs and adenylyl cyclase in living cells","year":2005,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; McGill University; Montreal Heart Institute; Western University","funders":"","keywords":"RGS2; Adenylyl cyclase; Heterotrimeric G protein; Gs alpha subunit; G protein; HEK 293 cells; Green fluorescent protein; Cell biology; Molecular biology; Luciferase; Signal transduction; Chemistry; Biology; Transfection; Receptor; GTPase-activating protein; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003529152,0.0003453951,0.0004323534,0.0002510599,0.0005254696,0.0007864123,0.0006011998,0.000572139,0.001646788],"category_scores_gemma":[0.0002756621,0.0003284928,0.0004514741,0.0002823984,0.0006338535,0.0006076168,0.0005904422,0.0008748886,0.00094788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001325082,"about_ca_system_score_gemma":0.0002935606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002203881,"about_ca_topic_score_gemma":0.003025337,"domain_scores_codex":[0.9997261,0.00004236587,0.00001311295,0.000075405,0.00008679294,0.00005619368],"domain_scores_gemma":[0.9998765,0.00003600306,0.00001633552,0.00003060504,0.00001170845,0.0000288387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001113266,0.00001462357,0.0001632526,0.00003929165,0.00001253653,0.0001294898,0.00004819061,0.0001372211,0.9977018,0.0005900431,0.0001817113,0.0008704789],"study_design_scores_gemma":[0.00003935832,0.00006801409,0.00344459,0.000008088485,0.00001884381,0.0003646017,0.00008033623,0.003103055,0.9844496,0.0003948462,0.008008717,0.00002007787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812149,0.002770493,0.008717061,0.0006120355,0.0001609908,0.00001817326,0.0003654528,0.0002593733,0.005881545],"genre_scores_gemma":[0.9817058,0.00149813,0.005914886,0.0003311275,0.00008779867,0.00004575083,0.0009980928,0.0001318036,0.009286707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002203881,"threshold_uncertainty_score":0.009614229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00497292064144097,"score_gpt":0.1929155418559729,"score_spread":0.1879426212145319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}