{"id":"W2054366592","doi":"10.1111/j.1399-302x.2009.00532.x","title":"<i>Porphyromonas gingivalis</i> mediates the shedding and proteolysis of complement regulatory protein CD46 expressed by oral epithelial cells","year":2009,"lang":"en","type":"article","venue":"Oral Microbiology and Immunology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; University of North Carolina at Chapel Hill","keywords":"Porphyromonas gingivalis; CD46; Biology; Proteolysis; Lipopolysaccharide; Microbiology; Secretion; Complement system; Recombinant DNA; Molecular biology; Antibody; Immunology; Biochemistry; Enzyme; Bacteria; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001383852,0.0003267297,0.0001842385,0.0001088608,0.0001520836,0.0003263617,0.00009887353,0.000193066,0.001662885],"category_scores_gemma":[0.0001066825,0.00007761245,0.0001792687,0.0001115784,0.0001505363,0.0001376423,0.000163327,0.0002442482,0.0006349643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002490499,"about_ca_system_score_gemma":0.0002065502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000776606,"about_ca_topic_score_gemma":0.0005194593,"domain_scores_codex":[0.9998835,0.00001739024,0.00001067912,0.00001703702,0.00002925297,0.0000421487],"domain_scores_gemma":[0.9999402,0.00001246542,0.00002020927,0.000009346451,0.00000896504,0.000008852149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001153481,0.00002306841,0.0004123008,0.00007839516,0.000002310955,0.0001110489,0.00001891705,0.00001932217,0.9981578,0.00003049302,0.00005022058,0.0009808928],"study_design_scores_gemma":[0.00001488112,0.0003256719,0.01652346,0.00001928754,0.00001191447,0.000916668,0.00006506219,0.0004601408,0.978773,0.00004655042,0.002839301,0.00000408971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926885,0.003489055,0.001571701,0.0001232918,0.00001752857,0.00003608221,0.0004499693,0.00003535878,0.001588563],"genre_scores_gemma":[0.9949622,0.001707081,0.001163528,0.00004971858,0.00001704811,0.00003089237,0.0005967831,0.000004796233,0.00146786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001662885,"threshold_uncertainty_score":0.005562901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008859781878449364,"score_gpt":0.2223170979380856,"score_spread":0.2134573160596363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}