{"id":"W2054403765","doi":"10.1007/s11095-012-0727-3","title":"Reversine, a 2,6-disubstituted Purine, as an Anti-cancer Agent in Differentiated and Undifferentiated Thyroid Cancer Cells","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ditmanson Medical Foundation Chia-Yi Christian Hospital; Beef Cattle Research Council; National Science Council","keywords":"Thyroid cancer; Cancer; Cancer cell; Cancer research; Purine; Medicine; Chemistry; Internal medicine; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007353288,0.000246781,0.0002440568,0.0001962492,0.0001509777,0.00007567975,0.0003695277,0.0002659404,0.000589923],"category_scores_gemma":[0.0001489775,0.000214646,0.00007032661,0.0004939929,0.0004164746,0.00002201419,0.0005782438,0.0007618961,0.00004904911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007749103,"about_ca_system_score_gemma":0.0001447607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005159351,"about_ca_topic_score_gemma":0.00007912947,"domain_scores_codex":[0.9966533,0.0004891318,0.0002602577,0.0006281373,0.0006622851,0.001306892],"domain_scores_gemma":[0.9984738,0.00004228293,0.00002957923,0.0003460734,0.0002129134,0.000895336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004431171,0.0007011793,0.01632843,0.00009597404,0.00008025699,0.00001233824,0.00004764611,0.00000245886,0.9786704,0.0001228767,0.001144789,0.002350546],"study_design_scores_gemma":[0.001579306,0.0001370317,0.01683344,0.00003972227,0.00002245609,0.000005447414,0.00003811573,0.0003665734,0.9669546,0.00004432906,0.01370116,0.0002777738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906738,0.007571997,0.00004609219,0.0005854869,0.0001331489,0.0005299075,0.00004876032,0.0000192267,0.000391517],"genre_scores_gemma":[0.9904959,0.007703644,0.00004160277,0.0002491129,0.0002520664,0.0001703591,0.0001550872,0.00004205009,0.0008901774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01255637,"threshold_uncertainty_score":0.8753011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1168809991818166,"score_gpt":0.4683843733437139,"score_spread":0.3515033741618973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}