{"id":"W2054403765","doi":"10.1007/s11095-012-0727-3","title":"Reversine, a 2,6-disubstituted Purine, as an Anti-cancer Agent in Differentiated and Undifferentiated Thyroid Cancer Cells","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ditmanson Medical Foundation Chia-Yi Christian Hospital; Beef Cattle Research Council; National Science Council","keywords":"Thyroid cancer; Cancer; Cancer cell; Cancer research; Purine; Medicine; Chemistry; Internal medicine; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002755183,0.000272192,0.0004022457,0.0004456966,0.0001955374,0.0003255975,0.0004330569,0.0004047555,0.001054511],"category_scores_gemma":[0.0001825455,0.000182118,0.0003168151,0.0003594907,0.00023369,0.0003222623,0.0001293777,0.0005195158,0.0002443029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003541018,"about_ca_system_score_gemma":0.0004066493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002726303,"about_ca_topic_score_gemma":0.003454864,"domain_scores_codex":[0.9998102,0.00005931592,0.00002335791,0.00003021476,0.0000419069,0.00003498816],"domain_scores_gemma":[0.9998435,0.00005264835,0.00001959943,0.00002808643,0.00002328982,0.00003299165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006874229,0.00007807658,0.0002145203,0.00008221542,0.00001115618,0.0001323616,0.00006884256,0.000281758,0.9938577,0.0002882343,0.00008145948,0.004216385],"study_design_scores_gemma":[0.00002637292,0.0008345635,0.001236177,0.000003303993,0.00002623745,0.0001217622,0.00001974647,0.0004869672,0.9954489,0.00001736321,0.001773616,0.000004981541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991109,0.0049854,0.0008055084,0.00006696361,0.00005293935,0.00002906181,0.0003711358,0.0001201158,0.002459903],"genre_scores_gemma":[0.9921889,0.002434053,0.001174619,0.00002947091,0.00001427144,0.00001324951,0.0005341812,0.00002483783,0.003586437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002726303,"threshold_uncertainty_score":0.005420923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1168809991818166,"score_gpt":0.4683843733437139,"score_spread":0.3515033741618973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}