{"id":"W2054511991","doi":"10.1074/jbc.m008187200","title":"Activation of Akt/Protein Kinase B in Epithelial Cells by theSalmonella typhimurium Effector SigD","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":190,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Effector; Protein kinase B; Cell biology; Biology; Kinase; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001790949,0.0001173341,0.0002007248,0.00001608802,0.00001661478,0.000007746561,0.0001710999,0.0001888922,0.0003402477],"category_scores_gemma":[0.00007958969,0.00008187704,0.0001246179,0.00007150763,0.0000835664,0.000004143094,0.00002785891,0.0001552982,0.000005190544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003408303,"about_ca_system_score_gemma":0.00005581182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002867918,"about_ca_topic_score_gemma":9.755391e-7,"domain_scores_codex":[0.999177,0.00005892102,0.0002862267,0.0001559092,0.0001390542,0.0001828601],"domain_scores_gemma":[0.9995442,0.00002574418,0.0001492738,0.0001268412,0.00005787695,0.00009608751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001140937,0.0002842977,0.0007902774,0.00002419267,0.0000378181,0.00001631654,0.000005256884,0.00001901986,0.9933161,2.437516e-7,0.0004373004,0.003928237],"study_design_scores_gemma":[0.001086432,0.0006132037,0.0006538418,0.00003270847,0.000004600965,0.0000107151,0.000009009666,0.000002515373,0.9929832,0.00004318362,0.00447799,0.00008261779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986998,0.0004964754,0.00001650954,0.00006121492,0.00001463229,0.00009230265,0.00005652857,0.000001842674,0.0005606582],"genre_scores_gemma":[0.9990252,0.0003103876,0.0000675191,0.00002507869,0.0001608893,0.000005883543,0.00004105485,0.000007047605,0.0003569996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00404069,"threshold_uncertainty_score":0.3725474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019517767647703,"score_gpt":0.256530966972276,"score_spread":0.246335789295799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}