{"id":"W2054519090","doi":"10.1038/ng.2900","title":"Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma","year":2014,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":195,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Biology; Lymphoma; Missense mutation; Cancer research; T-cell lymphoma; Frameshift mutation; Mutation; Gene; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001725223,0.0001671826,0.0001865151,0.00007100966,0.00003197031,0.0000123547,0.0001915963,0.000281321,0.000004360071],"category_scores_gemma":[0.0001868571,0.0001672453,0.00004303588,0.0001120638,0.0001102892,0.00000297002,0.0001467797,0.00008301263,0.000002542677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002331329,"about_ca_system_score_gemma":0.0001206888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005687395,"about_ca_topic_score_gemma":0.00003029331,"domain_scores_codex":[0.9989567,0.0000745432,0.0002755451,0.0003012485,0.0001825904,0.0002093094],"domain_scores_gemma":[0.9993517,0.00004468298,0.0001349564,0.0003217802,0.00006970539,0.00007718079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000385725,0.001264703,0.05613508,0.001050367,0.00007719872,0.00001389378,0.0003265785,0.0002253328,0.4684381,0.000595135,0.003002277,0.4684857],"study_design_scores_gemma":[0.002068703,0.0004870511,0.181642,0.00005689935,0.00003266807,0.00002085507,0.00002168755,0.0003398418,0.8092819,0.0005491328,0.005262482,0.0002367764],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9599039,0.03866231,0.0005679606,0.00006324803,0.0001772228,0.0002237086,0.00006391201,0.000007699602,0.0003300358],"genre_scores_gemma":[0.9879767,0.0005762955,0.01078741,0.0001877011,0.0001388913,0.00002193651,0.0002654714,0.00002226921,0.00002330747],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4682489,"threshold_uncertainty_score":0.6820067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004193126112541316,"score_gpt":0.2265253020102247,"score_spread":0.2223321758976834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}