{"id":"W2054529093","doi":"10.1002/cyto.b.21028","title":"Flow cytometry‐based assessment of mitoxantrone efflux from leukemic blasts varies with response to induction chemotherapy in acute myeloid leukemia","year":2012,"lang":"en","type":"article","venue":"Cytometry Part B Clinical Cytometry","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Mitoxantrone; Chemotherapy; Myeloid leukemia; Medicine; Internal medicine; Induction chemotherapy; Flow cytometry; Gastroenterology; Oncology; Pharmacology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.008269742,0.001037288,0.00296789,0.004893979,0.0001935592,0.0001039815,0.0009515121,0.001272589,0.001119995],"category_scores_gemma":[0.004702263,0.0008855014,0.0006131275,0.01165475,0.0009656408,0.0006872835,0.0004447365,0.003202586,0.0003792036],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004830512,"about_ca_system_score_gemma":0.003986131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001680606,"about_ca_topic_score_gemma":0.00001637733,"domain_scores_codex":[0.9889885,0.001555898,0.002899087,0.001704746,0.002695032,0.002156719],"domain_scores_gemma":[0.9884524,0.005719155,0.0008062291,0.002381084,0.0006915657,0.001949508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02866752,0.002240413,0.8403074,0.0002062573,0.001288183,0.0001734791,0.0002391038,0.0002111922,0.1135369,0.00001152074,0.00470623,0.008411813],"study_design_scores_gemma":[0.01805683,0.004219849,0.9199578,0.0006154494,0.000451105,0.00009652696,0.0003084414,0.002987781,0.04547529,0.00001228585,0.006931306,0.0008873293],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771426,0.0003260766,0.01648309,0.002073256,0.00100041,0.001961576,0.0003639269,0.0002621086,0.0003869926],"genre_scores_gemma":[0.9419465,0.0002339941,0.05228928,0.002323227,0.001676742,0.0002267631,0.0003467367,0.0002542762,0.0007024735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07965045,"threshold_uncertainty_score":0.9997931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04395661293656691,"score_gpt":0.3925688594367375,"score_spread":0.3486122465001705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}