{"id":"W2054533099","doi":"10.1038/cdd.2012.160","title":"SIGN-R1, a C-type lectin, enhances apoptotic cell clearance through the complement deposition pathway by interacting with C1q in the spleen","year":2012,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Konkuk University","keywords":"C-type lectin; Lectin pathway; Cell biology; Apoptosis; Lectin; Mannan-binding lectin; Complement C1q; Spleen; Chemistry; Complement system; Classical complement pathway; Complement (music); Biology; Immunology; Biochemistry; Immune system; Phenotype; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006000486,0.0005371359,0.0006283153,0.0006004803,0.0003132749,0.0005856677,0.0004734058,0.0006028794,0.002500493],"category_scores_gemma":[0.0003325573,0.000289379,0.0005327272,0.0001834705,0.000569136,0.0005067431,0.0003602957,0.001623217,0.0008475501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00080795,"about_ca_system_score_gemma":0.0006919694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001018997,"about_ca_topic_score_gemma":0.001488493,"domain_scores_codex":[0.9993867,0.0001622361,0.00003306998,0.00006867092,0.00013819,0.00021108],"domain_scores_gemma":[0.9996474,0.00005756861,0.00006710507,0.00003958912,0.0000566709,0.0001316342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004509472,0.00005261885,0.00008453494,0.00004979777,0.000004966272,0.00003726314,0.00001118531,0.00004347044,0.9982221,0.0001145296,0.00007362652,0.0008549371],"study_design_scores_gemma":[0.00007869871,0.0004792024,0.003691044,0.000009619714,0.00002258416,0.00022118,0.00003386185,0.001163675,0.9931521,0.0001008407,0.001039546,0.0000075232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913577,0.003079386,0.002970311,0.0003687285,0.00005268119,0.00002748299,0.0001657402,0.0001285985,0.001849359],"genre_scores_gemma":[0.9927891,0.0009872143,0.001800444,0.0001250883,0.00002997695,0.00003192424,0.0003583077,0.00004006879,0.003837923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002500493,"threshold_uncertainty_score":0.008365035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01668784678738634,"score_gpt":0.2374616336344126,"score_spread":0.2207737868470262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}