{"id":"W2054533099","doi":"10.1038/cdd.2012.160","title":"SIGN-R1, a C-type lectin, enhances apoptotic cell clearance through the complement deposition pathway by interacting with C1q in the spleen","year":2012,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Konkuk University","keywords":"C-type lectin; Lectin pathway; Cell biology; Apoptosis; Lectin; Mannan-binding lectin; Complement C1q; Spleen; Chemistry; Complement system; Classical complement pathway; Complement (music); Biology; Immunology; Biochemistry; Immune system; Phenotype; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000179455,0.0001356393,0.000131326,0.00002487188,0.0003052402,0.0000480035,0.00009815021,0.00006796703,0.00005495852],"category_scores_gemma":[0.000009930609,0.00007554767,0.00002814004,0.00009614447,0.00003926082,0.0002570602,0.00002621249,0.0001755059,0.00002097073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002719216,"about_ca_system_score_gemma":0.000009704453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001504966,"about_ca_topic_score_gemma":0.00003155033,"domain_scores_codex":[0.9990601,0.0002739277,0.0002037226,0.0001545516,0.0000505653,0.0002571357],"domain_scores_gemma":[0.9994844,0.0001725614,0.0001657429,0.0001382313,0.00002895174,0.0000101386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002943978,0.0004596014,0.019242,0.00005569158,0.00004161889,2.293168e-7,0.009525268,0.00001366311,0.9641294,0.0004012556,0.001010392,0.004826514],"study_design_scores_gemma":[0.001500101,0.0003926354,0.2134207,0.00007655823,0.0000896927,0.00001564913,0.00270277,0.0001945421,0.7762686,0.00009582859,0.005008611,0.0002343032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886391,0.004805806,0.004911138,0.0001261091,0.0003732836,0.0003265734,0.000002583458,0.00001487554,0.0008005349],"genre_scores_gemma":[0.9991286,0.0001558611,0.00005427136,0.0001335571,0.00003542214,0.00002636001,0.0002318766,0.000008713996,0.0002252913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1941787,"threshold_uncertainty_score":0.3080744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01668784678738634,"score_gpt":0.2374616336344126,"score_spread":0.2207737868470262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}