{"id":"W2054546131","doi":"10.1002/cbic.200700713","title":"A FACS‐Based Approach to Engineering Artificial Riboswitches","year":2008,"lang":"en","type":"article","venue":"ChemBioChem","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; McMaster University","keywords":"Riboswitch; Sorting; Computer science; Cell sorting; Computational biology; Information retrieval; Chemistry; Artificial intelligence; Biology; Gene; RNA; Cell; Algorithm; Biochemistry; Non-coding RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003864471,0.0004843636,0.0003165953,0.000365825,0.0004168256,0.000703832,0.0006154859,0.0005069188,0.002722956],"category_scores_gemma":[0.0003509331,0.0002648755,0.0003065577,0.0002622158,0.0004435485,0.0003324467,0.0003756149,0.001581777,0.001620047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006626185,"about_ca_system_score_gemma":0.0006330177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006541297,"about_ca_topic_score_gemma":0.0008941678,"domain_scores_codex":[0.9997031,0.00003612151,0.00003076306,0.00006460627,0.0001199619,0.0000454346],"domain_scores_gemma":[0.999797,0.00006449784,0.00002118354,0.0000310677,0.000061641,0.00002451458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004498468,0.0000354298,0.00004995202,0.0000471954,0.000005316856,0.00002363767,0.00001978694,0.0004348222,0.9913573,0.002005004,0.000296992,0.005679572],"study_design_scores_gemma":[0.00001113183,0.00005353701,0.00009602305,0.000002296837,0.000004894848,0.00006145218,0.000005994691,0.002326079,0.9911635,0.0003763761,0.005887847,0.00001087069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3335147,0.001048041,0.6400972,0.001109549,0.0005736472,0.001049923,0.002849169,0.004000018,0.01575773],"genre_scores_gemma":[0.6921263,0.001294699,0.2878394,0.0005245034,0.00006033258,0.0009115392,0.00236014,0.0003362866,0.01454674],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002722956,"threshold_uncertainty_score":0.009109199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02356155546418931,"score_gpt":0.2129188764191214,"score_spread":0.1893573209549321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}