{"id":"W2054577003","doi":"10.1016/j.bpj.2009.08.006","title":"Cell-Wall Interactions and the Selective Bacteriostatic Activity of a Miniature Oligo-Acyl-Lysyl","year":2009,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Israel Science Foundation","keywords":"Periplasmic space; Peptidoglycan; Bacterial outer membrane; Bacteria; Bacterial cell structure; Cytoplasm; Membrane; Chemistry; Gram-negative bacteria; Biophysics; Intracellular; Cell wall; Cell membrane; Lipid II; Cell envelope; Biochemistry; Lysis; Inner membrane; Escherichia coli; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009739109,0.0001322471,0.0002899017,0.00004433716,0.0003038095,0.0000365581,0.0001174035,0.00007600294,0.00006483452],"category_scores_gemma":[0.00003350157,0.00008081024,0.0001522174,0.00008458371,0.0003123617,0.0001699515,0.00003572213,0.0005741769,0.000018389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000209686,"about_ca_system_score_gemma":0.00003891395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004087919,"about_ca_topic_score_gemma":0.000004727396,"domain_scores_codex":[0.9992995,0.0001724564,0.0001680985,0.0001226181,0.00002988407,0.0002073956],"domain_scores_gemma":[0.9993699,0.0002418939,0.0002056859,0.00009550127,0.00006286241,0.00002415369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006824405,0.0002525496,0.00003202932,0.000006784118,0.00009087122,0.000002796984,0.001282151,8.312203e-7,0.9930263,0.0004115535,0.002158656,0.002053023],"study_design_scores_gemma":[0.003661581,0.0006209317,0.03537405,0.00007791791,0.0001721624,0.000449253,0.000701045,0.000031067,0.9539847,0.001086283,0.003599975,0.0002410094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970062,0.0001167929,0.0001552894,0.001984936,0.0001839339,0.00009299556,0.00001295816,0.00001020653,0.0004366316],"genre_scores_gemma":[0.998905,0.0001004361,0.00009468203,0.000329968,0.00008392138,0.000001310322,0.000003273117,0.000005951731,0.0004754565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03904159,"threshold_uncertainty_score":0.3295346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006301065877442624,"score_gpt":0.2267610766614557,"score_spread":0.2204600107840131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}