{"id":"W2054577003","doi":"10.1016/j.bpj.2009.08.006","title":"Cell-Wall Interactions and the Selective Bacteriostatic Activity of a Miniature Oligo-Acyl-Lysyl","year":2009,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Israel Science Foundation","keywords":"Periplasmic space; Peptidoglycan; Bacterial outer membrane; Bacteria; Bacterial cell structure; Cytoplasm; Membrane; Chemistry; Gram-negative bacteria; Biophysics; Intracellular; Cell wall; Cell membrane; Lipid II; Cell envelope; Biochemistry; Lysis; Inner membrane; Escherichia coli; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001312649,0.0001969347,0.0001466008,0.00006417581,0.0001184076,0.0003111004,0.0001798528,0.0002487395,0.0007996735],"category_scores_gemma":[0.0001881706,0.0001200374,0.0001280011,0.00006613282,0.0002072757,0.000173471,0.0001983583,0.0005058412,0.0002721001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001537714,"about_ca_system_score_gemma":0.0000672629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001669692,"about_ca_topic_score_gemma":0.0001685322,"domain_scores_codex":[0.9999361,0.00001273858,0.00000586074,0.00001472728,0.00001256839,0.00001803652],"domain_scores_gemma":[0.9998364,0.0000504924,0.00004186729,0.00001932269,0.000008042874,0.00004391916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005195683,0.000006533689,0.0001067913,0.000003901378,0.000001132217,0.00002854324,0.000005442893,0.00001497375,0.9995108,0.00003975831,0.00000646449,0.0002236684],"study_design_scores_gemma":[0.00001597768,0.0002310655,0.00452614,0.000001917825,0.000009887894,0.0002309694,0.00002720321,0.0008606914,0.9931563,0.000037018,0.0008985853,0.000004220464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992003,0.0001485305,0.0004133725,0.00003631873,0.000006851129,0.000002066983,0.00002059839,0.000006530103,0.000165409],"genre_scores_gemma":[0.9986078,0.00008197184,0.0005487604,0.00003147459,0.000006868578,0.000004093377,0.00007829167,0.000006008829,0.00063476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007996735,"threshold_uncertainty_score":0.002675235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006301065877442624,"score_gpt":0.2267610766614557,"score_spread":0.2204600107840131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}