{"id":"W2054635400","doi":"10.1007/s10555-014-9542-0","title":"Immunotherapy of melanoma: Present options and future promises","year":2015,"lang":"en","type":"review","venue":"Cancer and Metastasis Reviews","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; Vancouver Coastal Health Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Ipilimumab; Medicine; Melanoma; Immunotherapy; Clinical trial; Oncology; Immune system; Immunology; Nivolumab; Adjuvant; Monoclonal antibody; CTLA-4; Internal medicine; T cell; Antibody; Cancer research","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008707863,0.0008408084,0.001502444,0.00147434,0.0002819169,0.00131878,0.000881028,0.001357657,0.004097605],"category_scores_gemma":[0.000911283,0.0002710179,0.0005223008,0.001318059,0.0006399985,0.001864736,0.000853088,0.002765103,0.001630442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005677747,"about_ca_system_score_gemma":0.001104332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008121417,"about_ca_topic_score_gemma":0.00254676,"domain_scores_codex":[0.9998202,0.00003841563,0.00001951021,0.00002905391,0.00006346883,0.00002933246],"domain_scores_gemma":[0.9995729,0.0002270941,0.00004839845,0.00001010634,0.00008517538,0.00005626609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001103123,0.00007933413,0.0001464473,0.01150802,0.00007043686,0.0001163985,0.00004190475,0.0003690075,0.00169544,0.003604566,0.04727004,0.934988],"study_design_scores_gemma":[0.00004412626,0.0001369388,0.0005297887,0.004116477,0.0001326785,0.0006535542,0.00006793193,0.000158983,0.000331632,0.003136109,0.9906715,0.00002031302],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004498077,0.999024,0.00006633909,0.0003495648,0.0002056723,0.000001908247,0.000006581539,0.000004422376,0.0002965672],"genre_scores_gemma":[0.0004556678,0.998517,0.0001134871,0.0003267092,0.000273323,0.000003311507,0.00001358942,8.500859e-7,0.000296081],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004097605,"threshold_uncertainty_score":0.01370788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1540316203694242,"score_gpt":0.444403877725553,"score_spread":0.2903722573561288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}