{"id":"W2054649640","doi":"10.1038/cgt.2011.38","title":"Gap junctions in human glioblastomas: implications for suicide gene therapy","year":2011,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec; Hôpital de l'Enfant-Jésus; Hôtel-Dieu de Québec","funders":"","keywords":"Connexin; Suicide gene; Gap junction; Ganciclovir; Bystander effect; Cancer research; Genetic enhancement; Cell culture; Thymidine kinase; Biology; Herpes simplex virus; Kinase; U87; Glioblastoma; Gene; Intracellular; Virus; Virology; Immunology; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001155158,0.0001758878,0.0001679865,0.00007512129,0.0001335485,0.000009067055,0.0002281663,0.0001567061,0.0001692546],"category_scores_gemma":[0.000007065118,0.0001584413,0.0001219659,0.0001216079,0.00008583587,0.000003571405,0.00002615383,0.00006469538,0.000002875786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002914645,"about_ca_system_score_gemma":0.0001010894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003399212,"about_ca_topic_score_gemma":0.001236729,"domain_scores_codex":[0.9989994,0.00004251271,0.0002181437,0.0004014556,0.00003219762,0.000306324],"domain_scores_gemma":[0.999293,0.00001058544,0.00007615954,0.000456187,0.0001009511,0.00006307038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003090891,0.0001130486,0.01021671,0.000001820793,0.00007492381,3.226405e-7,0.0001423688,0.000009104861,0.9633109,0.000387275,0.001254726,0.02417973],"study_design_scores_gemma":[0.001839115,0.0008356991,0.06787147,0.000003896392,0.000006553174,0.000006495138,0.00002728297,0.000004430876,0.8129087,0.00127593,0.1149616,0.0002588376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872423,0.00921441,0.0017411,0.0004581258,0.0002377326,0.0005200266,0.00009326828,0.00002294126,0.0004701272],"genre_scores_gemma":[0.987357,0.008419954,0.0005558401,0.001539515,0.0004703299,0.0009222048,0.0001576312,0.00004060982,0.0005369639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1504022,"threshold_uncertainty_score":0.6461051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09519597322926458,"score_gpt":0.3403354758439688,"score_spread":0.2451395026147042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}