{"id":"W2054655480","doi":"10.1042/bj20082159","title":"Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition <i>in vivo</i> does not alter cardiac long-chain fatty acid uptake and oxidation rates","year":2009,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"ZonMw; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Carnitine palmitoyltransferase I; Carnitine; CD36; Internal medicine; Carnitine O-palmitoyltransferase; Endocrinology; Beta oxidation; Fatty acid; Flux (metallurgy); Sarcolemma; Chemistry; Myocyte; Biology; Biochemistry; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001338323,0.0006234769,0.0005541389,0.0002405481,0.0001852418,0.0003506598,0.0004471136,0.0004990924,0.002043158],"category_scores_gemma":[0.0001612302,0.0002576637,0.0004223535,0.0002221815,0.0005473334,0.0004432476,0.0002387847,0.001404052,0.000382899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005484542,"about_ca_system_score_gemma":0.0003558095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002084328,"about_ca_topic_score_gemma":0.00270583,"domain_scores_codex":[0.9997852,0.00001873134,0.0000241894,0.00005708497,0.00002935102,0.00008542697],"domain_scores_gemma":[0.9996623,0.00006301249,0.0001090888,0.00003889042,0.00002694267,0.00009981912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002292948,0.0001422762,0.0001547458,0.00004806751,0.00001447124,0.00004154176,0.00002090561,0.00008286104,0.9957713,0.00007505966,0.00007269276,0.001283143],"study_design_scores_gemma":[0.000112864,0.002151545,0.003179205,0.000008183699,0.00003779347,0.00007848634,0.0000441979,0.0006204406,0.9923725,0.00003190558,0.001353197,0.000009837274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961779,0.0006375114,0.0011277,0.0001393926,0.00009300179,0.00003936555,0.0007498186,0.0001025354,0.000932792],"genre_scores_gemma":[0.9897302,0.001055859,0.002022623,0.0001621894,0.00004558639,0.0001375403,0.002205516,0.00008283451,0.004557665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002084328,"threshold_uncertainty_score":0.006835043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008203587215658479,"score_gpt":0.2441925617622987,"score_spread":0.2359889745466402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}