{"id":"W2054655480","doi":"10.1042/bj20082159","title":"Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition <i>in vivo</i> does not alter cardiac long-chain fatty acid uptake and oxidation rates","year":2009,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"ZonMw; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Carnitine palmitoyltransferase I; Carnitine; CD36; Internal medicine; Carnitine O-palmitoyltransferase; Endocrinology; Beta oxidation; Fatty acid; Flux (metallurgy); Sarcolemma; Chemistry; Myocyte; Biology; Biochemistry; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003392623,0.0002484704,0.0002612636,0.00006954032,0.00009501679,0.00008440056,0.00009309594,0.0002536059,0.00004089197],"category_scores_gemma":[0.0000827259,0.0002016965,0.0001360401,0.00009435658,0.00006760844,0.00001348186,0.0000293667,0.000241228,0.000003017293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008405436,"about_ca_system_score_gemma":0.00005809161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007408186,"about_ca_topic_score_gemma":0.000009256945,"domain_scores_codex":[0.9984336,0.0001235433,0.0004313995,0.0003962888,0.0002327053,0.0003824903],"domain_scores_gemma":[0.9993979,0.00001118289,0.00009564481,0.0001900405,0.00008580925,0.0002194295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002059579,0.00007927373,0.001508293,0.000009906362,0.00002463317,0.00001247645,0.00005231949,0.000003699842,0.9916143,0.00001526956,0.0006594143,0.005814415],"study_design_scores_gemma":[0.001229459,0.0001679511,0.007519343,0.00003019674,0.00003617489,0.00005227228,0.00006710029,0.00001491959,0.9894552,0.0001267064,0.001025305,0.0002754197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958351,0.001456454,0.001215286,0.0008771266,0.0002640675,0.0001832961,0.00004373581,0.000009956413,0.0001150009],"genre_scores_gemma":[0.9962968,0.00139238,0.0003830772,0.0008893575,0.0008564362,0.000009624149,0.0001206441,0.00001801241,0.00003368276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006011051,"threshold_uncertainty_score":0.8224943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008203587215658479,"score_gpt":0.2441925617622987,"score_spread":0.2359889745466402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}