{"id":"W2054660342","doi":"10.1086/376609","title":"Loss of Kindlin-1, a Human Homolog of the Caenorhabditis elegans Actin–Extracellular-Matrix Linker Protein UNC-112, Causes Kindler Syndrome","year":2003,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":344,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; SickKids Foundation; Hospital for Sick Children","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Wellcome Trust","keywords":"Caenorhabditis elegans; Extracellular matrix; Linker; Cell biology; Actin; Chemistry; Biology; Genetics; Gene; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009242034,0.0005903753,0.0003004834,0.0005644875,0.0003042264,0.0002291271,0.0002441097,0.0004962144,0.000855537],"category_scores_gemma":[0.0003790621,0.0002751652,0.0002018654,0.0002602822,0.0005028194,0.0002387808,0.000331483,0.0005489089,0.0004405819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004073709,"about_ca_system_score_gemma":0.0002777737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001166178,"about_ca_topic_score_gemma":0.002489209,"domain_scores_codex":[0.9998654,0.00001424538,0.0000187392,0.00003640073,0.00004823647,0.00001694852],"domain_scores_gemma":[0.9997389,0.00005670734,0.000101134,0.00002610547,0.00001419621,0.00006290894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001972839,0.00002401061,0.001877296,0.00004821596,0.00002381082,0.002266459,0.00004811413,0.0002644751,0.9911946,0.0002401915,0.000462234,0.003353204],"study_design_scores_gemma":[0.0001210097,0.0002337588,0.05650194,0.00002924638,0.0001498064,0.03246774,0.0001781398,0.004012639,0.8986005,0.0006436774,0.007027975,0.00003359323],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959117,0.0005871517,0.001574461,0.0001462774,0.0000344254,0.00001231576,0.0003739907,0.000185737,0.001173978],"genre_scores_gemma":[0.9960829,0.0003011997,0.001534438,0.00004570836,0.000009567606,0.00001174475,0.0003576443,0.00004917695,0.001607537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001166178,"threshold_uncertainty_score":0.002955675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0138974187310447,"score_gpt":0.2884751912163793,"score_spread":0.2745777724853345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}