{"id":"W2054660342","doi":"10.1086/376609","title":"Loss of Kindlin-1, a Human Homolog of the Caenorhabditis elegans Actin–Extracellular-Matrix Linker Protein UNC-112, Causes Kindler Syndrome","year":2003,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":344,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; SickKids Foundation; Hospital for Sick Children","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Wellcome Trust","keywords":"Caenorhabditis elegans; Extracellular matrix; Linker; Cell biology; Actin; Chemistry; Biology; Genetics; Gene; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009148802,0.0002531752,0.0005270328,0.0001038947,0.0002246533,0.00001852098,0.001045898,0.0001467557,0.00007331318],"category_scores_gemma":[0.0001353509,0.0001604102,0.0003761186,0.0002879085,0.001950417,0.000004328564,0.0001787845,0.0005025912,0.000002757112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002375671,"about_ca_system_score_gemma":0.0002799821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004565869,"about_ca_topic_score_gemma":0.00003202056,"domain_scores_codex":[0.9973366,0.0008008422,0.0007691474,0.0002461456,0.0004307628,0.000416467],"domain_scores_gemma":[0.9973315,0.00004900492,0.001272571,0.000829172,0.0004056301,0.0001121124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000831314,0.0002189827,0.01471439,0.00002786106,0.0003193742,0.0000728489,0.0001731972,0.00007870576,0.9835681,0.000302108,0.000149353,0.0002919577],"study_design_scores_gemma":[0.0008806275,0.004108157,0.01516975,0.00008590607,0.0001675797,0.002321026,0.00060485,0.000002052249,0.972715,0.0006615273,0.003009209,0.0002743522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950472,0.004084173,0.0001562075,0.0001328539,0.0001026257,0.0003090556,0.00002015207,0.000002789766,0.0001450089],"genre_scores_gemma":[0.9975713,0.000176593,0.0004372934,0.00003629882,0.0001376515,0.00000748298,0.000007193576,0.0000428347,0.001583369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01085312,"threshold_uncertainty_score":0.7186394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0138974187310447,"score_gpt":0.2884751912163793,"score_spread":0.2745777724853345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}