{"id":"W2054719244","doi":"10.1038/nature13034","title":"Direct measurement of local oxygen concentration in the bone marrow of live animals","year":2014,"lang":"en","type":"article","venue":"Nature","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1142,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"National Institute of Biomedical Imaging and Bioengineering; National Heart, Lung, and Blood Institute","keywords":"Oxygen tension; Bone marrow; Stem cell; Haematopoiesis; Hypoxia (environmental); Homing (biology); Progenitor cell; Chemistry; Niche; Cell biology; Hematopoietic stem cell; Biology; Oxygen; Biophysics; Immunology; Pathology; Medicine; Biochemistry; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002564811,0.0002962143,0.0003075407,0.0003200044,0.0003479661,0.0003639337,0.0005220021,0.0004582692,0.001754539],"category_scores_gemma":[0.0002176081,0.0001887818,0.0001579499,0.0002448217,0.000814355,0.0004949204,0.0003749884,0.001216699,0.0003528059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002452025,"about_ca_system_score_gemma":0.0003312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001308954,"about_ca_topic_score_gemma":0.002161492,"domain_scores_codex":[0.9998741,0.00001753855,0.000003329863,0.00004532353,0.00003504649,0.00002458109],"domain_scores_gemma":[0.9998469,0.00004647063,0.00002835488,0.00001794065,0.00002014654,0.00004016743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001552504,0.00001262235,0.0005177207,0.00002942177,0.000006662501,0.00003006614,0.00004189496,0.00002729576,0.9972537,0.0002049407,0.00004669177,0.00167375],"study_design_scores_gemma":[0.00005055999,0.0005426763,0.01002555,0.00001590243,0.00004872556,0.0002608709,0.0001597895,0.0007852508,0.9849597,0.000408838,0.00273331,0.000008898066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8986436,0.008361301,0.08475753,0.0004949733,0.0002164476,0.0001162584,0.00074296,0.0002403808,0.006426638],"genre_scores_gemma":[0.9575518,0.004090973,0.02873237,0.0003243287,0.0001035338,0.0002280023,0.0007637497,0.00009706294,0.008108087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001754539,"threshold_uncertainty_score":0.005869567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007588183747259153,"score_gpt":0.233857541813146,"score_spread":0.2262693580658868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}