{"id":"W2054721620","doi":"10.1038/cdd.2013.191","title":"Rip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafish","year":2014,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; University of Washington","keywords":"Necroptosis; Cell biology; Programmed cell death; Biology; Zebrafish; Photoreceptor cell; Retina; Retinal degeneration; Visual phototransduction; Gene knockdown; Morpholino; Outer nuclear layer; Kinase; Apoptosis; Genetics; Gene; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001123138,0.0001690968,0.000138472,0.0000760185,0.00007284348,0.00005431167,0.00009373556,0.0001557297,0.00005767454],"category_scores_gemma":[0.00003211815,0.0001559861,0.00004971967,0.00005756504,0.0000198304,0.000008439843,0.0000584986,0.00007173623,0.00001692338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001048377,"about_ca_system_score_gemma":0.00002529616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003273134,"about_ca_topic_score_gemma":0.00005190983,"domain_scores_codex":[0.9990596,0.0000604383,0.0001991457,0.0003393843,0.0001095747,0.0002318163],"domain_scores_gemma":[0.9996275,0.00001340101,0.00007185722,0.0001574537,0.00003705303,0.00009278953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003225719,0.000254514,0.5170999,0.0001144151,0.00001479749,9.467058e-7,0.0002137827,0.00001034525,0.4768507,0.0001560263,0.00222589,0.002736129],"study_design_scores_gemma":[0.003437717,0.0002993363,0.5531417,0.00002447798,0.00003020791,0.000001216097,0.00007337303,0.0007996795,0.4232085,0.0006737295,0.01784521,0.0004648567],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852676,0.0004520549,0.001061549,0.00003039321,0.0001484366,0.0001773026,0.000003807259,0.00001259573,0.01284625],"genre_scores_gemma":[0.9965596,0.000472971,0.0003926254,0.0001304601,0.0000999486,0.00002060208,0.0004345273,0.00001629303,0.001872981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05364222,"threshold_uncertainty_score":0.6360927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007676096639719334,"score_gpt":0.2118251109841275,"score_spread":0.2041490143444081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}