{"id":"W2054745749","doi":"10.1007/s00430-014-0378-6","title":"Mouse models for therapeutic vaccination against hepatitis B virus","year":2014,"lang":"en","type":"review","venue":"Medical Microbiology and Immunology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Helmholtz-Alberta Initiative","keywords":"cccDNA; Hepatitis B virus; Virology; Immune system; Biology; Vaccination; Transgene; Hepatitis B; Humanized mouse; Immunology; Chronic infection; Antigen; Genetically modified mouse; Virus; HBsAg; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000665015,0.001263369,0.001476976,0.001852956,0.0001536985,0.0007063867,0.0007825419,0.000961228,0.002314838],"category_scores_gemma":[0.0005539237,0.0002862317,0.0004548116,0.0009734358,0.0005097521,0.0009555462,0.0005702293,0.002040915,0.0009708294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004949312,"about_ca_system_score_gemma":0.0007623727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006091819,"about_ca_topic_score_gemma":0.001519125,"domain_scores_codex":[0.999871,0.00002730337,0.0000211399,0.00002126389,0.00004436172,0.00001493817],"domain_scores_gemma":[0.9997581,0.0001104051,0.00005112783,0.000009392711,0.00004503628,0.0000259347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002990121,0.0001456464,0.0001779351,0.02117667,0.0001322118,0.0001834149,0.00002784303,0.0003197636,0.006757747,0.002787059,0.03187425,0.9361184],"study_design_scores_gemma":[0.0001211015,0.0002578514,0.0008688891,0.005479511,0.0004855163,0.001099786,0.00003747243,0.0001234862,0.002448524,0.002169383,0.9868757,0.00003271035],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001329988,0.9987703,0.0001516302,0.0001801825,0.0001734008,0.000006237249,0.0000217373,0.000007977357,0.00055566],"genre_scores_gemma":[0.0007698355,0.998082,0.0002392799,0.0002560995,0.0001429467,0.000009584624,0.00004380841,0.000001731506,0.0004546837],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002314838,"threshold_uncertainty_score":0.007743895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03570848319770595,"score_gpt":0.3203361190905147,"score_spread":0.2846276358928088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}