{"id":"W2054789512","doi":"10.1016/j.vaccine.2010.07.030","title":"A protein-based smallpox vaccine protects non-human primates from a lethal monkeypox virus challenge","year":2010,"lang":"en","type":"article","venue":"Vaccine","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":98,"is_retracted":false,"has_abstract":false,"ca_institutions":"Pfizer (Canada)","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases","keywords":"Monkeypox; Orthopoxvirus; Vaccinia; Virology; Smallpox; Variola virus; Poxviridae; Cowpox; Smallpox vaccine; Vaccination; Virus; Attenuated vaccine; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003477087,0.0004367153,0.0005722189,0.0002571769,0.000389048,0.00004835231,0.0006811685,0.0005708826,0.004562074],"category_scores_gemma":[0.0002163558,0.0003559171,0.0001666292,0.0002186759,0.00004342871,0.0001343525,0.000224864,0.001454082,0.002260815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004033377,"about_ca_system_score_gemma":0.0001718698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003385812,"about_ca_topic_score_gemma":0.00312032,"domain_scores_codex":[0.9975954,0.0001622702,0.0004554354,0.0006978599,0.0001102592,0.0009787959],"domain_scores_gemma":[0.9985006,0.0001325468,0.0001727563,0.0008959723,0.0001553967,0.0001426541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006672661,0.0005358617,0.00103613,0.00006026953,0.0001605345,0.00006736849,0.000129863,0.000001012344,0.991285,0.0001878236,0.001444677,0.004424205],"study_design_scores_gemma":[0.006891914,0.000830829,0.01935293,0.0000741896,0.00003472886,0.00002019234,0.00001973939,0.00004973236,0.9354896,0.0005474439,0.03623431,0.000454389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933524,0.001153176,0.0001025972,0.001546664,0.0003223937,0.001702648,0.0001759787,0.0002797289,0.00136447],"genre_scores_gemma":[0.9964182,0.00001856024,0.0004260408,0.0001704128,0.0002650456,0.0005293948,0.0003548302,0.00006786406,0.001749586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05579539,"threshold_uncertainty_score":0.9998893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01404113057703408,"score_gpt":0.2683891041606754,"score_spread":0.2543479735836413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}