{"id":"W2054803067","doi":"10.1021/ja054472v","title":"A Route to Annulated Indoles via a Palladium-Catalyzed Tandem Alkylation/Direct Arylation Reaction","year":2005,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":352,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Norbornene; Palladium; Aryl; Alkylation; Tandem; Catalysis; Alkyl; Ring (chemistry); Annulation; Organic chemistry; Combinatorial chemistry; Medicinal chemistry; Polymerization","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001424598,0.0003858279,0.0002138298,0.0001990536,0.0001882438,0.0001691273,0.0005145692,0.000203186,0.001370061],"category_scores_gemma":[0.00009501704,0.0002127571,0.0001937312,0.0001623827,0.0001672003,0.0002512268,0.0002427866,0.0009034778,0.0009692869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002711786,"about_ca_system_score_gemma":0.0003937578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006259696,"about_ca_topic_score_gemma":0.001717394,"domain_scores_codex":[0.9999256,0.000007881518,0.000006196324,0.00001827886,0.00002066649,0.00002137663],"domain_scores_gemma":[0.9999417,0.000006774339,0.0000148037,0.00001091366,0.00001251311,0.00001324813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005772471,0.00008615215,0.0001401459,0.000135711,0.00001256722,0.000241915,0.00007804218,0.0003011589,0.9818163,0.001185587,0.0003160096,0.01562877],"study_design_scores_gemma":[0.00004228529,0.0005371316,0.0008299142,0.00001237624,0.00002727939,0.0007173943,0.00002018651,0.001102307,0.9759528,0.0002349971,0.02050436,0.00001911609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7717318,0.007860343,0.1794607,0.0004311531,0.0002412443,0.0005115179,0.001070964,0.00142208,0.03727023],"genre_scores_gemma":[0.9268886,0.004795175,0.05522092,0.0001315561,0.00002762246,0.0001312536,0.0006227504,0.00008953945,0.0120925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001370061,"threshold_uncertainty_score":0.004583359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396674880845129,"score_gpt":0.2781398979765154,"score_spread":0.2641731491680641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}