{"id":"W2054868225","doi":"10.4161/cc.4.12.2250","title":"The GAR Motif of 53BP1 is Arginine Methylated by PRMT1 and is Necessary for 53BP1 DNA Binding Activity","year":2005,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"","keywords":"Biology; Arginine; Molecular biology; Methyltransferase; DNA damage; DNA repair; DNA; Methylation; Protein arginine methyltransferase 5; Binding site; Cell biology; Biochemistry; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001121339,0.0002973514,0.0002996461,0.0001432215,0.0002213738,0.0002222008,0.0001474776,0.0001965131,0.001498991],"category_scores_gemma":[0.0002008304,0.0001579427,0.0001910905,0.00009902394,0.0002328704,0.0001755873,0.0002521355,0.00035079,0.0008737044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003362366,"about_ca_system_score_gemma":0.0002043798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005434722,"about_ca_topic_score_gemma":0.0006774444,"domain_scores_codex":[0.9998585,0.00002174194,0.000009680701,0.00003515213,0.00003663492,0.00003836105],"domain_scores_gemma":[0.9998603,0.00001640488,0.00005290296,0.00001647176,0.00001194778,0.0000419405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005216612,0.000004178485,0.0001709168,0.00001399105,0.000001557395,0.00006188751,0.000004644573,0.00002212842,0.9986801,0.00005098705,0.00001856315,0.0009188428],"study_design_scores_gemma":[0.00001278637,0.0001307353,0.01711632,0.000006126793,0.00001125928,0.0007945229,0.00002368393,0.0005881453,0.9770821,0.0001151569,0.004114194,0.000004967736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902796,0.002497833,0.005059169,0.0001827468,0.00003750187,0.00001586913,0.0003032339,0.000203183,0.00142071],"genre_scores_gemma":[0.994895,0.0005514239,0.002226922,0.00002759721,0.000008937443,0.00001039079,0.0004608352,0.00002795449,0.001790987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001498991,"threshold_uncertainty_score":0.005014658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005269096020792363,"score_gpt":0.237406689916753,"score_spread":0.2321375938959606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}