{"id":"W2054872872","doi":"10.1074/jbc.m404488200","title":"The Proline-rich Homeodomain Protein Recruits Members of the Groucho/Transducin-like Enhancer of Split Protein Family to Co-repress Transcription in Hematopoietic Cells","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Directorate for Biological Sciences; Medical Research Council; Fonds de Recherche du Québec - Santé; University of Bristol","keywords":"Psychological repression; Homeobox; Transcription factor; Biology; Cell biology; Enhancer; Chromatin immunoprecipitation; Repressor; Immunoprecipitation; DNA-binding protein; Molecular biology; Genetics; Gene; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001401021,0.0003572648,0.0002425481,0.0001851883,0.0001491766,0.0002907255,0.0002090277,0.0001938285,0.000541025],"category_scores_gemma":[0.0001222619,0.0001662064,0.0002060917,0.0001250942,0.0002938896,0.0001596261,0.0004592928,0.0005272404,0.0005092351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002129294,"about_ca_system_score_gemma":0.0001261897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002049498,"about_ca_topic_score_gemma":0.0003073851,"domain_scores_codex":[0.9998094,0.00003428824,0.00001048395,0.00004592274,0.0000572729,0.0000425126],"domain_scores_gemma":[0.9999151,0.00001452992,0.00002043149,0.000012166,0.000007345844,0.00003035837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003266513,0.000006978068,0.000224031,0.00001567668,0.000002254124,0.00006363483,0.000008090215,0.00004037003,0.9988881,0.00007966259,0.00001670124,0.0006218647],"study_design_scores_gemma":[0.00001934318,0.0001408027,0.01994634,0.000004771082,0.00001205438,0.001160254,0.00005086399,0.003162792,0.9727948,0.0001527252,0.002547666,0.000007569325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914982,0.001774195,0.005443595,0.0000879312,0.00001826853,0.00001791778,0.0001143283,0.00007593427,0.0009695872],"genre_scores_gemma":[0.9943265,0.0006433254,0.00252714,0.00005709097,0.00001206265,0.00001608919,0.0003681417,0.00001724232,0.00203234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000541025,"threshold_uncertainty_score":0.001809955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01433748877591773,"score_gpt":0.2525045384973595,"score_spread":0.2381670497214418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}