{"id":"W2054931684","doi":"10.1016/j.immuni.2007.05.014","title":"Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression","year":2007,"lang":"en","type":"article","venue":"Immunity","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":360,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences","funders":"National Institute of Allergy and Infectious Diseases; National High-tech Research and Development Program; National Institute of General Medical Sciences; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Uehara Memorial Foundation","keywords":"Vesicular stomatitis virus; Biology; Virology; Dicer; microRNA; Viral replication; Interferon; Caenorhabditis elegans; RNA interference; Small interfering RNA; Antiviral protein; Phosphoprotein; Virus; Genome; Gene; Vesicular Stomatitis; RNA; RNA virus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000341811,0.00159088,0.0008050154,0.001918757,0.0004048794,0.0007399945,0.0007620681,0.001201874,0.004266571],"category_scores_gemma":[0.0004538216,0.0007714145,0.0007508895,0.0004161944,0.001546064,0.0005974014,0.0007014467,0.002301369,0.001071249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005095495,"about_ca_system_score_gemma":0.0003232349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004703897,"about_ca_topic_score_gemma":0.0007050551,"domain_scores_codex":[0.9993105,0.0001002642,0.00009692504,0.0001842421,0.0001673731,0.0001406657],"domain_scores_gemma":[0.9984488,0.0001223613,0.0006747571,0.0001767966,0.00005031347,0.000526818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003436367,0.00002772463,0.0001444017,0.0000266989,0.000008939081,0.0001704109,0.00001351078,0.0000349279,0.9986939,0.0001043107,0.00004887086,0.000382709],"study_design_scores_gemma":[0.0001231166,0.0003809355,0.01118848,0.00002132505,0.00006398043,0.002198009,0.00007643642,0.0008365493,0.9832199,0.0003108112,0.001546749,0.00003376423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918636,0.001090845,0.003146937,0.0003265428,0.0001052815,0.00005669811,0.001524598,0.0005439804,0.001341504],"genre_scores_gemma":[0.9880379,0.0007892122,0.003198,0.0001373638,0.00004066098,0.000147731,0.001015396,0.0003237085,0.006310161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004266571,"threshold_uncertainty_score":0.01427305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01217699363155527,"score_gpt":0.2730544353244822,"score_spread":0.2608774416929269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}