{"id":"W2054931684","doi":"10.1016/j.immuni.2007.05.014","title":"Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression","year":2007,"lang":"en","type":"article","venue":"Immunity","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":360,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences","funders":"National Institute of Allergy and Infectious Diseases; National High-tech Research and Development Program; National Institute of General Medical Sciences; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Uehara Memorial Foundation","keywords":"Vesicular stomatitis virus; Biology; Virology; Dicer; microRNA; Viral replication; Interferon; Caenorhabditis elegans; RNA interference; Small interfering RNA; Antiviral protein; Phosphoprotein; Virus; Genome; Gene; Vesicular Stomatitis; RNA; RNA virus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004478595,0.0001354747,0.0001363984,0.00009452402,0.00009287611,0.00002203205,0.0001215491,0.0001301978,0.0000252083],"category_scores_gemma":[0.0001042856,0.0001344438,0.00005021105,0.0001524834,0.00003643712,0.000007939885,0.0002031481,0.0001092232,0.00003218676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003521947,"about_ca_system_score_gemma":0.00002331685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005322875,"about_ca_topic_score_gemma":0.004211666,"domain_scores_codex":[0.9990667,0.00008798595,0.0002119513,0.0002957543,0.0001017633,0.0002358414],"domain_scores_gemma":[0.9993712,0.00001645323,0.00003840949,0.000378745,0.00007563314,0.000119532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001907105,0.0001202996,0.01716622,0.00001384912,0.00000837819,0.000005601251,0.0006804829,0.00002313827,0.9768144,6.23247e-7,0.0005956806,0.004380602],"study_design_scores_gemma":[0.0002081515,0.0003606972,0.3492501,0.00003254959,0.000004129821,0.000009110454,0.0001684243,0.000008317678,0.6478502,0.000006366877,0.001976341,0.0001256042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977058,0.0002383409,0.00132391,0.00007896897,0.0001392163,0.0002603919,0.00001821114,0.00001300993,0.000222147],"genre_scores_gemma":[0.998754,0.00008594507,0.0003746731,0.0006265666,0.00004057951,0.00001444095,0.00002626605,0.00001032142,0.00006717828],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3320839,"threshold_uncertainty_score":0.8046629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01217699363155527,"score_gpt":0.2730544353244822,"score_spread":0.2608774416929269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}