{"id":"W2054993171","doi":"10.1089/10430340050016148","title":"High-Efficiency Retroviral Transduction of Mammalian Cells on Positively Charged Surfaces","year":2000,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Heart, Lung, and Blood Institute; U.S. Public Health Service; Dr. Mildred Scheel Stiftung für Krebsforschung","keywords":"Transduction (biophysics); Haematopoiesis; Biology; Cell culture; CD34; Retrovirus; Genetic enhancement; Transfection; Cord blood; Viral vector; Molecular biology; Green fluorescent protein; Cell biology; CD40; Stem cell; Immunology; In vitro; Cytotoxic T cell; Gene; Recombinant DNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000305573,0.0002223349,0.0002129601,0.00008358961,0.0001608939,0.00001944767,0.0003147172,0.0001419212,0.001777405],"category_scores_gemma":[0.000001790778,0.000208451,0.0001413485,0.0001413099,0.0001566621,0.000005120877,0.000009939502,0.0001255524,0.00006769299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002147686,"about_ca_system_score_gemma":0.00004981274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007434472,"about_ca_topic_score_gemma":0.00003561388,"domain_scores_codex":[0.9984336,0.0002093718,0.0002635544,0.000440575,0.0002999466,0.0003529607],"domain_scores_gemma":[0.999308,0.000006021074,0.00006276863,0.0004680914,0.00007536257,0.00007974067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003591698,0.0002821567,0.00004511868,0.000005802309,0.00005903538,0.000002802631,0.0001579056,0.0008581452,0.9818611,0.00002057828,0.0001976635,0.01291802],"study_design_scores_gemma":[0.001484815,0.0101286,0.002443358,0.000006555018,0.000005142549,0.000002916056,0.00001642418,0.00001109855,0.9844222,0.00004096537,0.001222075,0.0002158598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980624,0.0008229326,0.00002292533,0.00009354405,0.00008190147,0.0003333189,0.00005512208,0.0000216913,0.0005061673],"genre_scores_gemma":[0.9955435,0.001106536,0.00009214065,0.0001972256,0.0002497447,0.00001746269,0.0001257394,0.00004807231,0.002619566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01270215,"threshold_uncertainty_score":0.9991351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01922855154002279,"score_gpt":0.2781285158312504,"score_spread":0.2588999642912276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}