{"id":"W2055006617","doi":"10.1073/pnas.0906539106","title":"Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research","keywords":"Histone octamer; Chromatin; Histone; Histone-modifying enzymes; Histone H2A; Histone H1; Histone code; Histone methyltransferase; Biology; Cell biology; Chromatin remodeling; Histone acetyltransferase; Acetylation; Nucleosome; Biochemistry; Chemistry; Molecular biology; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001999429,0.00004248799,0.00005747976,0.00002707074,0.00005648603,0.000008071962,0.0001597055,0.00006484196,5.011514e-7],"category_scores_gemma":[0.00004448318,0.0000270718,0.0000176352,0.0001165354,0.0002316781,0.00001012972,0.00006057452,0.00004458418,7.819506e-9],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005253075,"about_ca_system_score_gemma":0.00001335551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003189089,"about_ca_topic_score_gemma":0.00000109358,"domain_scores_codex":[0.999536,0.000004664809,0.0001303509,0.0001040544,0.0001751265,0.00004977816],"domain_scores_gemma":[0.9997501,0.00000762076,0.0001688111,0.000006768033,0.00005717599,0.000009539001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008254382,0.000007335708,0.01479456,0.00001148588,0.000002644362,5.166465e-10,0.00007337676,0.00006815133,0.9819056,0.002928436,0.00001422469,0.000185929],"study_design_scores_gemma":[0.0001513484,0.000041904,0.4093968,0.00002435833,0.000003460628,0.000005707376,0.0001017436,0.001053483,0.5503998,0.03877672,0.00001250878,0.00003207502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998631,0.0001988014,0.000001043586,0.000805549,0.000005057151,0.00008249987,0.00001030879,6.087587e-7,0.000265109],"genre_scores_gemma":[0.9988581,0.00003724353,0.0009572921,0.0001228313,0.00001259227,5.345582e-7,4.313617e-7,0.000001145032,0.000009828325],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4315057,"threshold_uncertainty_score":0.1103956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007484543030234508,"score_gpt":0.2384248123033501,"score_spread":0.2309402692731156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}