{"id":"W2055022262","doi":"10.1016/s0168-8278(00)80360-8","title":"Early perturbations in keratin and actin gene expression and fibrillar organisation in griseofulvin-fed mouse liver","year":2000,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec; Université du Québec à Trois-Rivières","funders":"","keywords":"Griseofulvin; Keratin; Actin; Messenger RNA; Biology; Gene expression; Hepatocyte; Keratin 8; Keratin 7; Cell biology; Keratin 6A; Gene; Cytoskeleton; Molecular biology; Cell; Pathology; Intermediate filament; Immunology; Immunohistochemistry; Cytokeratin; Biochemistry; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002305972,0.00007906616,0.0001611074,0.0001002749,0.00003626017,0.00001256678,0.00006500337,0.000194962,0.00009475601],"category_scores_gemma":[0.0000891751,0.00006727232,0.00002384064,0.00005055173,0.00007516424,0.000008556337,0.00003769431,0.0001479927,0.000002556002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001416891,"about_ca_system_score_gemma":0.00005895898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003260865,"about_ca_topic_score_gemma":0.000071706,"domain_scores_codex":[0.9991929,0.0002059982,0.0002455869,0.0001466555,0.00006219137,0.0001466991],"domain_scores_gemma":[0.9997134,0.00003441881,0.00007189541,0.00008625341,0.00003851352,0.0000555644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002453641,0.00003479161,0.2440787,0.000004644675,0.000008498312,0.0000595014,0.0001883943,0.00000441569,0.7528567,0.000002983689,0.0001605722,0.002355458],"study_design_scores_gemma":[0.002412373,0.001006288,0.159188,0.00002547754,0.0000106721,0.002136013,0.0001484945,0.0002468477,0.8315802,0.0001094232,0.002945365,0.0001908573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973429,0.002197278,0.00003356764,0.0002293535,0.00002596049,0.00007056837,0.000002116666,0.000001272895,0.0000969223],"genre_scores_gemma":[0.9961191,0.002896823,0.00059029,0.00006633521,0.00006176249,0.000002072896,0.00001060154,0.000007732611,0.0002452362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08489071,"threshold_uncertainty_score":0.2743286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0097602829097726,"score_gpt":0.2444896654888373,"score_spread":0.2347293825790647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}