{"id":"W2055046713","doi":"10.1089/nat.2010.0275","title":"Cytosine-Phosphate-Guanine Oligodeoxynucleotides Containing GACGTT Motifs Enhance the Immune Responses Elicited by Keyhole Limpet Hemocyanin Antigen in Dairy Cattle","year":2011,"lang":"en","type":"article","venue":"Nucleic Acid Therapeutics","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; National Science Council","keywords":"Keyhole limpet hemocyanin; CpG Oligodeoxynucleotide; Hemocyanin; Biology; CpG site; Antigen; Immune system; Adjuvant; Molecular biology; Antibody; Immunology; Biochemistry; DNA methylation; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002263152,0.0003961106,0.0003001739,0.0002978434,0.000130191,0.0002704127,0.0001531075,0.0003212267,0.0005296816],"category_scores_gemma":[0.0001976978,0.0001548655,0.0001967219,0.0001781434,0.000232184,0.0001378611,0.0001372817,0.0003852443,0.0001376029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003893327,"about_ca_system_score_gemma":0.0001917311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001633262,"about_ca_topic_score_gemma":0.002276124,"domain_scores_codex":[0.9997786,0.00004317729,0.00001218624,0.00004403384,0.00005266633,0.0000693675],"domain_scores_gemma":[0.9998751,0.00003726111,0.00002920678,0.000004095664,0.0000146518,0.0000396557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001590983,0.00002769083,0.0002849597,0.00003536412,0.000003052387,0.00002046669,0.00001918143,0.00004485647,0.9987538,0.00001208691,0.000009349173,0.0006301168],"study_design_scores_gemma":[0.00006017479,0.00246455,0.01717766,0.00001413005,0.00005382163,0.0001658332,0.0001000995,0.0009096396,0.9773129,0.00005408538,0.001675869,0.00001117119],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978985,0.001096992,0.0004278131,0.00002860537,0.00001278411,0.00001199041,0.00006880466,0.0000138572,0.0004407273],"genre_scores_gemma":[0.9975503,0.0006745242,0.0007040258,0.00005011053,0.000009511135,0.00001502222,0.0001445605,0.000005348519,0.0008465646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001633262,"threshold_uncertainty_score":0.003247559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02320271290698256,"score_gpt":0.252195380438418,"score_spread":0.2289926675314354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}