{"id":"W2055069441","doi":"10.1161/circulationaha.109.869156","title":"Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor","year":2010,"lang":"en","type":"review","venue":"Circulation","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":363,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Eye Institute; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; Medical Research Council; National Institutes of Health; Vetenskapsrådet; Stockholms Läns Landsting; Knut och Alice Wallenbergs Stiftelse; Hjärt-Lungfonden; ZonMw; National Center for Research Resources; Fondation Leducq; King's College London; University of Leeds; National Institute on Aging; National Institute for Health and Care Research; Erasmus Medisch Centrum; Directorate for Biological Sciences; GlaxoSmithKline; Cedars-Sinai Medical Center; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Biotechnology and Biological Sciences Research Council; Wellcome Trust; European Commission; School of Medicine, Boston University; Royal Society; National Institute of Diabetes and Digestive and Kidney Diseases; Sanofi; University of Minnesota; Scottish Government; Uppsala Universitet; Erasmus Universiteit Rotterdam; Institute of Genetics; AstraZeneca; U.S. Public Health Service; Eli Lilly and Company","keywords":"Medicine; Von Willebrand factor; Factor (programming language); Internal medicine; Genetics; Platelet; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009809746,0.0007522391,0.0005453044,0.0008406122,0.0004067413,0.0008929562,0.0007221912,0.0008672358,0.002953327],"category_scores_gemma":[0.003522068,0.0003197619,0.000963556,0.00133538,0.0004419414,0.0002551124,0.000335933,0.0006391119,0.0002367614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002419445,"about_ca_system_score_gemma":0.0005042573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002008755,"about_ca_topic_score_gemma":0.001953706,"domain_scores_codex":[0.9991794,0.0001595458,0.00007289795,0.0003941901,0.0001297582,0.00006422605],"domain_scores_gemma":[0.9976783,0.001101099,0.0007198167,0.000161019,0.0001597667,0.0001800013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0030923,0.0002899049,0.923307,0.0003018628,0.004622589,0.008213847,0.0004018871,0.001461629,0.0284602,0.001250446,0.001618614,0.02697966],"study_design_scores_gemma":[0.0008422653,0.0006991047,0.9637582,0.00007530964,0.004415194,0.01519242,0.0001667564,0.004219673,0.004267029,0.003546516,0.002764102,0.00005342143],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9922807,0.002616117,0.002943716,0.0004894495,0.00008698474,0.00001954362,0.000806143,0.00005596043,0.0007013952],"genre_scores_gemma":[0.995321,0.0004243356,0.003039647,0.0001035185,0.0001170118,0.00002556929,0.0004306463,0.00001536788,0.0005228569],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002953327,"threshold_uncertainty_score":0.009879827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09812245794160268,"score_gpt":0.3188182025406933,"score_spread":0.2206957445990906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}