{"id":"W2055069783","doi":"10.3390/ijms15022494","title":"Survivin as a Preferential Target for Cancer Therapy","year":2014,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Survivin; Programmed cell death; Autophagy; Apoptosis; Cancer; Cancer research; Cancer cell; Immunotherapy; Medicine; Inhibitor of apoptosis; Biology; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006357878,0.0001871491,0.0004225094,0.0001685751,0.00005473449,0.00009913598,0.0008140702,0.0001737794,0.00004991643],"category_scores_gemma":[0.00007150383,0.0001292814,0.0005760139,0.00007077304,0.0000812522,0.000007194732,0.0000696622,0.00008902524,0.000002165024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002454915,"about_ca_system_score_gemma":0.0005569887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001077116,"about_ca_topic_score_gemma":0.000005357558,"domain_scores_codex":[0.9985551,0.0001035518,0.0004597836,0.0002475,0.0004900127,0.0001440203],"domain_scores_gemma":[0.9986898,0.00002572353,0.0007084748,0.0001054798,0.0004117496,0.00005877263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003931692,0.00004620658,0.00000188182,0.0001340893,0.00042384,0.000003931465,0.000009760759,0.0001667475,0.005523898,0.0006985714,0.000374143,0.9925776],"study_design_scores_gemma":[0.0002938081,0.0004951382,9.026849e-7,0.0006332673,0.00006905149,0.00008770107,0.000004058429,0.00002816222,0.004881694,0.0007103449,0.9926406,0.0001553366],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006827796,0.9767165,0.0200204,0.00007812073,0.002049219,0.0002269621,0.00002648936,0.000002106606,0.0001974409],"genre_scores_gemma":[0.001484323,0.9951035,0.001910612,0.00009064699,0.001034596,0.00002422184,0.00005766657,0.00002026752,0.0002740992],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9924223,"threshold_uncertainty_score":0.5271941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03785930264343027,"score_gpt":0.3782248180218574,"score_spread":0.3403655153784271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}