{"id":"W2055069783","doi":"10.3390/ijms15022494","title":"Survivin as a Preferential Target for Cancer Therapy","year":2014,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Survivin; Programmed cell death; Autophagy; Apoptosis; Cancer; Cancer research; Cancer cell; Immunotherapy; Medicine; Inhibitor of apoptosis; Biology; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004668185,0.0007103521,0.001170068,0.001912466,0.0002659193,0.0009486208,0.0009282398,0.001181505,0.002509746],"category_scores_gemma":[0.0004456328,0.0002697383,0.0004089881,0.001439743,0.000462058,0.001311848,0.0005842285,0.002372772,0.001976948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008565195,"about_ca_system_score_gemma":0.0006687721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006378219,"about_ca_topic_score_gemma":0.001156678,"domain_scores_codex":[0.9998233,0.00003194599,0.00002385119,0.00003976498,0.00006193636,0.00001927844],"domain_scores_gemma":[0.9998569,0.00005029759,0.00001988583,0.000006109446,0.00004781479,0.00001889059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009300656,0.00008292127,0.0002421842,0.01361096,0.00007969404,0.0006430327,0.00008296445,0.0005459714,0.007585837,0.01095975,0.04658749,0.9194862],"study_design_scores_gemma":[0.00001179953,0.00007564144,0.0003702429,0.001101448,0.00004843154,0.001755179,0.0000279919,0.00009773721,0.001333079,0.001523016,0.9936418,0.00001367288],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001756064,0.9975646,0.0002630411,0.0003061412,0.0003070986,0.000005737428,0.00001562363,0.00001023504,0.001352064],"genre_scores_gemma":[0.001388823,0.9967226,0.0002536707,0.0002807324,0.000214493,0.00000921028,0.00003348122,0.0000024424,0.001094552],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002509746,"threshold_uncertainty_score":0.00839591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03785930264343027,"score_gpt":0.3782248180218574,"score_spread":0.3403655153784271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}