{"id":"W2055302859","doi":"10.1042/bj20040469","title":"The role of the <i>LRPPRC</i> (leucine-rich pentatricopeptide repeat cassette) gene in cytochrome oxidase assembly: mutation causes lowered levels of COX (cytochrome <i>c</i> oxidase) I and COX III mRNA","year":2004,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto; Centre Hospitalier Universitaire Sainte-Justine; Hospital for Sick Children","funders":"","keywords":"Cytochrome c oxidase; Molecular biology; Biology; Mitochondrion; Cytochrome; Mitochondrial DNA; Biochemistry; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007964559,0.0005472375,0.0001578608,0.000326883,0.0003135554,0.0002480671,0.0002370535,0.0005905387,0.001528274],"category_scores_gemma":[0.0002138213,0.0001363745,0.0001826785,0.0001576354,0.0004167741,0.00009730748,0.0001106615,0.0003156363,0.0004000099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001082538,"about_ca_system_score_gemma":0.0004435029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03148007,"about_ca_topic_score_gemma":0.03216297,"domain_scores_codex":[0.9999011,0.00001540521,0.000007899031,0.00002682244,0.00002454252,0.00002432476],"domain_scores_gemma":[0.9998313,0.00003499103,0.00005390265,0.00001005042,0.00001891225,0.00005075627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001603646,0.00001742677,0.002445761,0.00002635639,0.00001033925,0.001514939,0.00006807558,0.00007892696,0.9943119,0.00007614642,0.00008588933,0.001203844],"study_design_scores_gemma":[0.00009919457,0.0007600585,0.3354543,0.00003902416,0.0001383375,0.02755683,0.000357132,0.003208119,0.6257915,0.0001616453,0.006390802,0.00004302847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998454,0.0004065151,0.0003406898,0.00008661507,0.000007898265,0.000006519123,0.0002120126,0.00003278573,0.0004529716],"genre_scores_gemma":[0.9981993,0.0001218437,0.0005221159,0.00003709441,0.000005199553,0.00000550708,0.0002859688,0.000015716,0.0008071815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03148007,"threshold_uncertainty_score":0.0625937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009127007319790194,"score_gpt":0.2416828855051651,"score_spread":0.2325558781853749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}