{"id":"W2055302859","doi":"10.1042/bj20040469","title":"The role of the <i>LRPPRC</i> (leucine-rich pentatricopeptide repeat cassette) gene in cytochrome oxidase assembly: mutation causes lowered levels of COX (cytochrome <i>c</i> oxidase) I and COX III mRNA","year":2004,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto; Centre Hospitalier Universitaire Sainte-Justine; Hospital for Sick Children","funders":"","keywords":"Cytochrome c oxidase; Molecular biology; Biology; Mitochondrion; Cytochrome; Mitochondrial DNA; Biochemistry; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004371586,0.0002455874,0.0003333095,0.00007439264,0.0001808418,0.00004073318,0.0003484009,0.0002681067,0.00002020641],"category_scores_gemma":[0.0003530385,0.0001659881,0.0001780741,0.0002671801,0.0003000082,0.0000140442,0.0001719909,0.0003416922,0.000002475242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006156441,"about_ca_system_score_gemma":0.0002634792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006989483,"about_ca_topic_score_gemma":0.00006767385,"domain_scores_codex":[0.9980265,0.0002015568,0.0007442925,0.0003579475,0.0003208547,0.000348794],"domain_scores_gemma":[0.9986315,0.00008415837,0.0004753814,0.0004243552,0.0002329416,0.0001516684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003825278,0.0001170174,0.0008846481,0.00001601949,0.00005496888,0.00003410034,0.0001017416,0.00006840453,0.9973877,0.00003201152,0.0006896278,0.0002312428],"study_design_scores_gemma":[0.002630008,0.0003043344,0.007371333,0.00005922496,0.00005366695,0.001487274,0.0002015793,0.000006536638,0.9865913,0.0002897209,0.000815769,0.0001892193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957851,0.002772138,0.0003293193,0.0003748721,0.0002340301,0.0003057793,0.00006664899,0.000006026078,0.0001261072],"genre_scores_gemma":[0.9982092,0.0005065394,0.0005017807,0.0003227637,0.0002934434,0.00001303958,0.00002839451,0.00002550611,0.00009937523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01079636,"threshold_uncertainty_score":0.6768799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009127007319790194,"score_gpt":0.2416828855051651,"score_spread":0.2325558781853749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}