{"id":"W2055346625","doi":"10.1155/2010/613504","title":"Application of “omics” to Prion Biomarker Discovery","year":2010,"lang":"lv","type":"review","venue":"Journal of Biomedicine and Biotechnology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"","keywords":"Biomarker discovery; Biomarker; Computational biology; Proteomics; Disease; Omics; Genomics; Biology; Prion protein; Bioinformatics; Medicine; Genome; Gene; Pathology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001650718,0.001179763,0.002543343,0.003657347,0.0003541089,0.001756037,0.001257581,0.001742955,0.001646651],"category_scores_gemma":[0.001293794,0.000390686,0.0008095063,0.00344403,0.001309611,0.002213658,0.001092469,0.002187022,0.001274555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001326813,"about_ca_system_score_gemma":0.001030862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009327773,"about_ca_topic_score_gemma":0.001087231,"domain_scores_codex":[0.9994841,0.0001422402,0.00004922576,0.00008014491,0.0002134505,0.00003092385],"domain_scores_gemma":[0.9990371,0.0005663104,0.00008666615,0.0000484025,0.0002084878,0.00005288145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007885194,0.0001250897,0.0004669946,0.01311814,0.0002894615,0.0007031168,0.000167261,0.001338722,0.01116129,0.02404418,0.01876825,0.9297386],"study_design_scores_gemma":[0.00002873215,0.0001776399,0.001938218,0.003166492,0.0001614698,0.002317466,0.0001877657,0.001048584,0.005508681,0.02687854,0.9585069,0.00007950954],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004083011,0.9908302,0.004624344,0.001508609,0.0005481062,0.00002568796,0.00004361134,0.00003902442,0.001972143],"genre_scores_gemma":[0.002298045,0.9897593,0.005523806,0.0008517627,0.0005351646,0.00003613243,0.00005845379,0.000005405265,0.0009318779],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003657347,"threshold_uncertainty_score":0.009626746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088368754711671,"score_gpt":0.2942990799217323,"score_spread":0.2834153923746155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}