{"id":"W2055383185","doi":"10.1021/bi201161k","title":"The Enzymatic Activities of the <i>Escherichia coli</i> Basic Aliphatic Amino Acid Decarboxylases Exhibit a pH Zone of Inhibition","year":2011,"lang":"en","type":"article","venue":"Biochemistry","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Arginine decarboxylase; Lysine decarboxylase; Escherichia coli; Ornithine decarboxylase; Lysine; Biochemistry; Enzyme; Ornithine decarboxylase antizyme; Carboxy-lyases; Amino acid; Aromatic L-amino acid decarboxylase; Biology; Arginine; Chemistry; Putrescine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001272669,0.0001506991,0.0001570783,0.00001118455,0.0001080624,0.000008891307,0.0003016076,0.0001071477,0.00001310849],"category_scores_gemma":[0.00009304585,0.0001012291,0.0001339778,0.0001414151,0.0003926842,0.000004313801,0.0001394032,0.00006923099,0.000001469588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007055889,"about_ca_system_score_gemma":0.0001081095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003256903,"about_ca_topic_score_gemma":0.00001072366,"domain_scores_codex":[0.9991325,0.00004487664,0.000294297,0.000199817,0.0001506396,0.0001778446],"domain_scores_gemma":[0.998932,0.00002837426,0.0002721572,0.0006593163,0.00006370226,0.0000444707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003051366,0.0001090809,0.0002506965,0.00007591839,0.00003867894,1.422955e-7,0.00007923625,3.144811e-7,0.9981145,0.0001371405,0.0006357952,0.0005280042],"study_design_scores_gemma":[0.000262232,0.00003321349,0.001390301,0.00003808494,0.0000577866,0.000004401114,0.0002950718,0.000009101451,0.996642,0.0001052738,0.001052129,0.0001103883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953094,0.002165557,0.0003213008,0.00005362912,0.00006139143,0.0001823878,0.00007524421,0.000007936745,0.001823161],"genre_scores_gemma":[0.9986025,0.0001810319,0.0002829678,0.00008057363,0.00009696162,0.00008156039,0.0000313522,0.00001601769,0.000627043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0032931,"threshold_uncertainty_score":0.4128004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01034153197072202,"score_gpt":0.2099290645174198,"score_spread":0.1995875325466978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}