{"id":"W2055426083","doi":"10.1002/pbc.21937","title":"Hits and misses in targeting pediatric cancers","year":2009,"lang":"en","type":"letter","venue":"Pediatric Blood & Cancer","topic":"Gastrointestinal Tumor Research and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre","funders":"","keywords":"GiST; Medicine; Imatinib; Interstitial cell of Cajal; Imatinib mesylate; Platelet-derived growth factor receptor; Oncology; Internal medicine; Tyrosine kinase; Tyrosine-kinase inhibitor; Chemotherapy; Stromal tumor; Stromal cell; Cancer research; Cancer; Immunohistochemistry; Growth factor; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003639815,0.0005384578,0.0007806136,0.0008129125,0.0008985572,0.002904666,0.0009578057,0.002158132,0.02157736],"category_scores_gemma":[0.00788923,0.0002639526,0.0005021725,0.0007484404,0.001353846,0.00392347,0.003475549,0.003921452,0.007899085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00250281,"about_ca_system_score_gemma":0.001532392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008453904,"about_ca_topic_score_gemma":0.002259071,"domain_scores_codex":[0.9975976,0.0007932901,0.0001267271,0.0003064295,0.0008966227,0.0002792444],"domain_scores_gemma":[0.9962912,0.001424186,0.0004838161,0.0001671936,0.0006666537,0.0009669271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000795249,0.0001288812,0.007914679,0.002441688,0.0002244117,0.001421238,0.0007430035,0.001098101,0.003687758,0.05672543,0.2212464,0.7035731],"study_design_scores_gemma":[0.0001016994,0.0005386188,0.002641959,0.00117707,0.0001370353,0.003645689,0.0007209472,0.0003928271,0.002141036,0.02578303,0.9626918,0.00002827769],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.0360405,0.5424421,0.02664799,0.2009296,0.01376132,0.0002581346,0.001364493,0.001536607,0.1770194],"genre_scores_gemma":[0.3627998,0.4165922,0.02081809,0.118092,0.01711763,0.0004273941,0.001784413,0.0008903276,0.06147819],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.02157736,"threshold_uncertainty_score":0.07218343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01848811247230705,"score_gpt":0.2920285506350161,"score_spread":0.2735404381627091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}