{"id":"W2055449363","doi":"10.1002/jcp.22626","title":"Enzymatic activity of sperm proprotein convertase is important for mammalian fertilization","year":2011,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Sperm; Capacitation; Acrosome reaction; Human fertilization; Acrosome; Biology; Andrology; Zona pellucida; Epididymis; Subtilisin; Chemistry; Enzyme; Cell biology; Biochemistry; Oocyte; Botany; Anatomy; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002058248,0.0005101405,0.0003571403,0.0003364702,0.0001330149,0.000340351,0.0001399468,0.0002679139,0.001083027],"category_scores_gemma":[0.0002897351,0.0001717953,0.0002969489,0.0002527922,0.000178398,0.0001646585,0.0001602484,0.0003279846,0.0003108931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002655185,"about_ca_system_score_gemma":0.0002291512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00074475,"about_ca_topic_score_gemma":0.0004802682,"domain_scores_codex":[0.9997459,0.00003210076,0.0000290637,0.00005173255,0.0001028767,0.00003836269],"domain_scores_gemma":[0.9998485,0.00002868358,0.00005666555,0.000008577971,0.00003499704,0.00002254382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001322316,0.00001405017,0.002120936,0.00009928077,0.00002303433,0.0001706579,0.000008787971,0.0001047511,0.993182,0.00008394961,0.00004434994,0.004015869],"study_design_scores_gemma":[0.00001346496,0.0002780876,0.02916284,0.00001063382,0.00003848434,0.0009562226,0.00002028465,0.0009235822,0.9651436,0.00008914394,0.003353699,0.00001004053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788697,0.01310328,0.005643106,0.0001224716,0.00004416851,0.00002650544,0.0004516123,0.0001299351,0.001609116],"genre_scores_gemma":[0.9885051,0.004125445,0.003617927,0.00003463839,0.00001985471,0.00002018694,0.0006332241,0.00001318362,0.003030527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001083027,"threshold_uncertainty_score":0.003623068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03572248922951483,"score_gpt":0.2542479624464765,"score_spread":0.2185254732169617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}