{"id":"W2055449363","doi":"10.1002/jcp.22626","title":"Enzymatic activity of sperm proprotein convertase is important for mammalian fertilization","year":2011,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Sperm; Capacitation; Acrosome reaction; Human fertilization; Acrosome; Biology; Andrology; Zona pellucida; Epididymis; Subtilisin; Chemistry; Enzyme; Cell biology; Biochemistry; Oocyte; Botany; Anatomy; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002254031,0.0001022066,0.0003967524,0.00009924883,0.00002358215,0.000001857947,0.00005736377,0.00009572382,0.0004169862],"category_scores_gemma":[0.0001701086,0.00007403096,0.0001965418,0.00006677859,0.00006255641,0.0000730916,0.00001039513,0.0001136452,0.000004497258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002814542,"about_ca_system_score_gemma":0.0001134009,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002163188,"about_ca_topic_score_gemma":0.000001282151,"domain_scores_codex":[0.9991332,0.00004597017,0.0004450081,0.0001057709,0.0001381467,0.000131928],"domain_scores_gemma":[0.9988046,0.00003132132,0.0006007128,0.0001650234,0.0003165251,0.00008184532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001489721,0.0003757109,0.00233975,0.000291933,0.000105375,0.00002794133,0.0003425621,8.579601e-7,0.9939257,0.0001426969,0.0001617463,0.0007960029],"study_design_scores_gemma":[0.001622177,0.002052195,0.04045334,0.00007890558,0.0002564442,0.0001181423,0.00005434793,0.00080731,0.9527234,0.001581688,0.0001818214,0.00007024207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991602,0.0001860006,0.007429881,0.00009019898,0.0002331328,0.0003592639,0.000004209745,0.000005563275,0.00008972484],"genre_scores_gemma":[0.998135,0.00001708159,0.00146426,0.00009650086,0.0001615979,0.00000544809,0.000008580605,0.00001449883,0.00009707276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04120232,"threshold_uncertainty_score":0.4565707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03572248922951483,"score_gpt":0.2542479624464765,"score_spread":0.2185254732169617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}