{"id":"W2055463878","doi":"10.2337/dc11-2081","title":"Zinc Transporter-8 Autoantibodies Improve Prediction of Type 1 Diabetes in Relatives Positive for the Standard Biochemical Autoantibodies","year":2012,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; U.S. National Library of Medicine; Juvenile Diabetes Research Foundation International; National Institutes of Health; National Center for Research Resources; American Diabetes Association","keywords":"Autoantibody; Medicine; Diabetes mellitus; Type 1 diabetes; Internal medicine; Type 2 diabetes; Endocrinology; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001967669,0.0002026697,0.0002704757,0.00005004216,0.00008995899,0.00001596143,0.0001528127,0.0001940962,0.000006473539],"category_scores_gemma":[0.0001507525,0.0001572337,0.000175464,0.0001256226,0.0001875945,0.00001839458,0.00004693532,0.0001055567,0.000001824583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002696426,"about_ca_system_score_gemma":0.0000456307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004546966,"about_ca_topic_score_gemma":0.000006878955,"domain_scores_codex":[0.9988151,0.00004346914,0.0002752722,0.0002495454,0.0001326454,0.0004839568],"domain_scores_gemma":[0.9993095,0.0001012457,0.0001253087,0.0002080525,0.0002019887,0.00005392193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004703633,0.00005624385,0.6786221,0.0001069499,0.0002023642,5.189492e-8,0.0009026578,0.00001568619,0.3174405,0.00006842431,0.0006042387,0.001933756],"study_design_scores_gemma":[0.000984598,0.000689263,0.3018464,0.0001188472,0.0001668631,5.219789e-8,0.003135453,0.0001730307,0.6882379,0.00009451016,0.004283166,0.0002698707],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828315,0.01393485,0.00002193887,0.0001155242,0.0003420695,0.0004376054,0.002016485,0.00001905717,0.0002809569],"genre_scores_gemma":[0.9981323,0.0002980757,0.0001594735,0.00006792932,0.0001355468,0.00006228723,0.001074558,0.00002983514,0.00004002976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3767757,"threshold_uncertainty_score":0.6411803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005843289432640629,"score_gpt":0.230428294995669,"score_spread":0.2245850055630284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}