{"id":"W2055524078","doi":"10.2174/156720111795256129","title":"Biphasic Vesicles for Topical Delivery of Interferon Alpha in Human Volunteers and Treatment of Patients with Human Papillomavirus Infections","year":2011,"lang":"en","type":"article","venue":"Current Drug Delivery","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Canadian Institutes of Health Research","keywords":"Zeta potential; Vesicle; Interferon; Human skin; Alpha interferon; Medicine; Peripheral blood mononuclear cell; In vivo; Human papillomavirus; Papillomaviridae; Chemistry; Pathology; Immunology; In vitro; Internal medicine; Biology; Biochemistry; Nanoparticle; Materials science; Nanotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006784653,0.00017524,0.0003401943,0.0002103598,0.0001102183,0.00000362318,0.00009764102,0.00008052473,0.00007923172],"category_scores_gemma":[0.000006022169,0.0001401282,0.00009484424,0.00007670904,0.0003147974,0.0001061497,0.00003197446,0.00008320748,0.000003110804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005559946,"about_ca_system_score_gemma":0.00003112941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005745906,"about_ca_topic_score_gemma":0.0001838822,"domain_scores_codex":[0.9990718,0.0001183069,0.0003617316,0.0002022855,0.0000274051,0.0002185145],"domain_scores_gemma":[0.9994885,0.00008627977,0.0001347673,0.0001868306,0.00008944343,0.00001414287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004492635,0.003985429,0.6191677,0.0001150728,0.0005046964,0.000001053138,0.006399178,0.0000012358,0.2802524,0.0003724338,0.0001571357,0.08455096],"study_design_scores_gemma":[0.01023857,0.006900832,0.6284105,0.0002773093,0.00015491,0.000002524838,0.0005035137,0.000002115803,0.3492298,0.00009181255,0.003875678,0.0003124854],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990799,0.008403789,0.00001584673,0.000003916633,0.0002433615,0.0004299989,0.0000599963,0.00001580346,0.00002827333],"genre_scores_gemma":[0.9992319,0.0004829869,0.00001532785,0.000004514507,0.000007964843,0.00005205244,0.00009115344,0.00001341547,0.0001006579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08423847,"threshold_uncertainty_score":0.5714265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02818294300687148,"score_gpt":0.2618150872522625,"score_spread":0.2336321442453911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}