{"id":"W2055524078","doi":"10.2174/156720111795256129","title":"Biphasic Vesicles for Topical Delivery of Interferon Alpha in Human Volunteers and Treatment of Patients with Human Papillomavirus Infections","year":2011,"lang":"en","type":"article","venue":"Current Drug Delivery","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Canadian Institutes of Health Research","keywords":"Zeta potential; Vesicle; Interferon; Human skin; Alpha interferon; Medicine; Peripheral blood mononuclear cell; In vivo; Human papillomavirus; Papillomaviridae; Chemistry; Pathology; Immunology; In vitro; Internal medicine; Biology; Biochemistry; Nanoparticle; Materials science; Nanotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003079324,0.0001732152,0.0002504815,0.0001365423,0.0001040565,0.0002453655,0.0001194575,0.0002990116,0.0007300694],"category_scores_gemma":[0.000332053,0.00007252536,0.000111014,0.00007903804,0.0001005539,0.0001286543,0.0002076412,0.0002224972,0.000301511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001433555,"about_ca_system_score_gemma":0.0001519323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001788787,"about_ca_topic_score_gemma":0.0001962281,"domain_scores_codex":[0.9998999,0.00004728609,0.000006667502,0.00001498861,0.00001717202,0.00001396303],"domain_scores_gemma":[0.9999391,0.00001380289,0.00001928309,0.000004389647,0.000008705836,0.00001467877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.008180018,0.0006284869,0.005560717,0.0006362055,0.00004929466,0.00106215,0.0001779664,0.0004089098,0.8022725,0.0004684299,0.0009974509,0.1795578],"study_design_scores_gemma":[0.004144194,0.0575057,0.05498644,0.0003936471,0.0004174545,0.01918768,0.0006009453,0.007001913,0.7760323,0.0006552835,0.0789935,0.00008091528],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9596117,0.02844189,0.008813536,0.000351771,0.0001492921,0.000491203,0.0001447618,0.0001083317,0.001887519],"genre_scores_gemma":[0.9902441,0.004238675,0.004159244,0.0001128301,0.00003134889,0.0002120232,0.0001260759,0.000009367071,0.0008663447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007300694,"threshold_uncertainty_score":0.0024423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02818294300687148,"score_gpt":0.2618150872522625,"score_spread":0.2336321442453911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}