{"id":"W2055583355","doi":"10.1371/journal.pbio.0040021","title":"Intronic Binding Sites for hnRNP A/B and hnRNP F/H Proteins Stimulate Pre-mRNA Splicing","year":2006,"lang":"en","type":"article","venue":"PLoS Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":226,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"RNA splicing; Intron; Biology; Exon; Alternative splicing; Polypyrimidine tract; Precursor mRNA; Exonic splicing enhancer; Minigene; RNA-binding protein; Messenger RNA; Exon skipping; SR protein; Splice site mutation; Genetics; Protein splicing; Cell biology; Molecular biology; RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002059794,0.0001777892,0.0002134008,0.00008378795,0.0001723681,0.00003369778,0.0001645161,0.0002064526,0.00001242328],"category_scores_gemma":[0.0001652343,0.0001536534,0.0000678487,0.00006879678,0.0001226061,0.000005457087,0.000155949,0.0001180534,0.00000749335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002182952,"about_ca_system_score_gemma":0.00005079589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001162819,"about_ca_topic_score_gemma":0.0001486798,"domain_scores_codex":[0.9986368,0.00005989492,0.0002215776,0.0004660674,0.00006221338,0.0005534306],"domain_scores_gemma":[0.9994738,0.00005342249,0.00007631435,0.0002416883,0.00007019663,0.00008461533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001410508,0.00004862321,0.01554142,0.00004957692,0.00005687164,0.000001399122,0.00000986619,0.00004648688,0.9820127,0.0004685981,0.0002723415,0.001351058],"study_design_scores_gemma":[0.001755547,0.001645928,0.004077272,0.00004089662,0.00003909524,0.00002140684,0.0000309523,0.0052574,0.9772151,0.00121342,0.008282992,0.0004199906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952276,0.001023059,0.002500105,0.0002388661,0.00003797522,0.0006927789,0.00004564103,0.00002574578,0.0002082224],"genre_scores_gemma":[0.995538,0.000110017,0.001843874,0.00008081096,0.0004511949,0.0001271705,0.0003012445,0.00002895021,0.001518712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01146415,"threshold_uncertainty_score":0.6265805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01524764449769351,"score_gpt":0.2818408122372391,"score_spread":0.2665931677395456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}