{"id":"W2055623303","doi":"10.3389/fphys.2010.00014","title":"Biochemistry and occurrence of O-demethylation in plant metabolism","year":2010,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"Plant Gene Expression Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Benzylisoquinoline; Demethylation; Biochemistry; Enzyme; Biosynthesis; Opium Poppy; DNA demethylation; Hydroxylation; Metabolism; Chemistry; Biology; Papaver; DNA methylation; Gene; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001256008,0.00008859662,0.0002018293,0.0001001,0.00001054334,0.000002041486,0.0001281353,0.0001780424,0.000007536694],"category_scores_gemma":[0.0001031308,0.00008460918,0.00003067625,0.0001046547,0.0001098481,0.000002806409,0.00007225887,0.0001397716,3.722628e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002974645,"about_ca_system_score_gemma":0.00003110923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002028672,"about_ca_topic_score_gemma":0.00003519912,"domain_scores_codex":[0.9993262,0.00004787628,0.0001854119,0.000259871,0.00004598968,0.0001346828],"domain_scores_gemma":[0.9996619,0.00001040516,0.00008207844,0.0001959853,0.00001811381,0.00003156547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006384587,0.00002897919,0.01853799,0.00001053051,0.00001315345,7.117218e-7,0.00002328998,0.00002800549,0.9741835,0.00001108979,0.006028319,0.0010706],"study_design_scores_gemma":[0.0004463425,0.00001975481,0.04385477,0.000007861384,0.00000865114,0.000004286161,0.00005724529,0.0005771581,0.950147,0.0004257197,0.004326614,0.0001245664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987913,0.0004455515,0.0002294851,0.00002559129,0.0002741468,0.00004748049,0.00007467701,0.000002350871,0.0001093917],"genre_scores_gemma":[0.9965428,0.0002079905,0.002864931,0.00003928348,0.00004429397,0.000008185642,0.0002558823,0.000003743334,0.00003291281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02531678,"threshold_uncertainty_score":0.3450262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00451801132630444,"score_gpt":0.2252859951931805,"score_spread":0.2207679838668761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}