{"id":"W2055663112","doi":"10.1371/journal.pone.0089968","title":"Polymeric Micelles for Apoptosis-Targeted Optical Imaging of Cancer and Intraoperative Surgical Guidance","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; National Institutes of Health; University of Wisconsin-Madison","keywords":"In vivo; Ovarian cancer; Ethylene glycol; Micelle; Apoptosis; Paclitaxel; PEG ratio; Chemistry; Cancer research; Cancer; Medicine; Biology; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002678189,0.00011703,0.0002901853,0.00003933433,0.00007212331,0.00003469886,0.0001251822,0.00002605706,0.0001176742],"category_scores_gemma":[0.0001457163,0.0001040461,0.00003000325,0.00009893669,0.0002202364,0.0001303413,0.00005345486,0.00004829478,0.00001453559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002396807,"about_ca_system_score_gemma":0.00004081499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001046788,"about_ca_topic_score_gemma":0.00001073386,"domain_scores_codex":[0.9989012,0.00006261702,0.0002647352,0.0002815466,0.0002140578,0.0002758067],"domain_scores_gemma":[0.9991911,0.0003284382,0.00008264446,0.0001646461,0.0001363613,0.00009682727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001305558,0.0003228721,0.003167756,0.00008169756,0.00002120241,6.234698e-7,0.0001195629,0.00001591425,0.994748,0.0005170631,0.00004225564,0.0008324721],"study_design_scores_gemma":[0.0007596252,0.00007623948,0.0004406762,0.0001099506,0.00007436882,6.650076e-7,0.00003606699,0.006798251,0.9914824,0.00005217336,0.00003501157,0.0001345266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966039,0.001782148,0.0002810404,0.000842924,0.00005638024,0.0002345093,0.00004043799,0.0000415269,0.0001171399],"genre_scores_gemma":[0.9896743,0.00004387331,0.009889087,0.0001157567,0.0001131866,0.00008544097,0.000002815531,0.00001627183,0.00005927834],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009608046,"threshold_uncertainty_score":0.4242879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01746765389329654,"score_gpt":0.2439179185498563,"score_spread":0.2264502646565597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}