{"id":"W2055707604","doi":"10.1101/gad.1881810","title":"Functional interaction between telomere protein TPP1 and telomerase","year":2010,"lang":"en","type":"article","venue":"Genes & Development","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; Arizona State University; Helen Hay Whitney Foundation","keywords":"Biology; Telomere; Telomerase; Telomere-binding protein; Genetics; DNA-binding protein; Molecular biology; Cell biology; Cancer research; DNA; Gene; Transcription factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001466835,0.0004561039,0.0001309484,0.0001503723,0.0001611347,0.0002593582,0.0002327869,0.0002932937,0.001835292],"category_scores_gemma":[0.0002436771,0.0001871373,0.0002334731,0.0001005847,0.0001983551,0.0002082517,0.0003500462,0.0003560306,0.0006223907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000238597,"about_ca_system_score_gemma":0.0001235474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001526121,"about_ca_topic_score_gemma":0.0002322965,"domain_scores_codex":[0.9998965,0.00002032912,0.000008339047,0.00002786267,0.00002549241,0.00002141854],"domain_scores_gemma":[0.9998587,0.000036921,0.00004273535,0.00001534477,0.000007123869,0.00003907735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006724436,0.00001313412,0.0004887346,0.0000321855,0.000004846727,0.0001524999,0.000008542837,0.00005029593,0.9979389,0.0001303769,0.00002628803,0.001086848],"study_design_scores_gemma":[0.00001829452,0.0002505613,0.01890686,0.00001019433,0.00002472033,0.002572064,0.00002068154,0.001212372,0.9726835,0.0001754385,0.004118178,0.000007178847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941779,0.001863316,0.00234256,0.00008544917,0.0000164061,0.00001222502,0.0001410104,0.00006467968,0.001296466],"genre_scores_gemma":[0.9960459,0.0004041365,0.001099015,0.00004229304,0.00001067497,0.00001588061,0.0005093384,0.00001068778,0.001862042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001835292,"threshold_uncertainty_score":0.006139636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02453958288751804,"score_gpt":0.2619083479543028,"score_spread":0.2373687650667848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}