{"id":"W2055707604","doi":"10.1101/gad.1881810","title":"Functional interaction between telomere protein TPP1 and telomerase","year":2010,"lang":"en","type":"article","venue":"Genes & Development","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; Arizona State University; Helen Hay Whitney Foundation","keywords":"Biology; Telomere; Telomerase; Telomere-binding protein; Genetics; DNA-binding protein; Molecular biology; Cell biology; Cancer research; DNA; Gene; Transcription factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002768509,0.0002981414,0.0003544194,0.0002560267,0.0002658785,0.00005253414,0.00009390132,0.0001710737,0.000577748],"category_scores_gemma":[0.00007386402,0.0002616163,0.00006017593,0.0002512813,0.0001120897,0.0001713469,0.00009930546,0.0004557719,0.0002821478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008171249,"about_ca_system_score_gemma":0.0003728003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000391796,"about_ca_topic_score_gemma":0.00006863162,"domain_scores_codex":[0.9981306,0.00002834429,0.000465344,0.0005205575,0.0004478777,0.0004073289],"domain_scores_gemma":[0.9990118,0.0000543066,0.0001168408,0.0002996892,0.0001642684,0.0003531169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0001596606,0.0001402096,0.1795081,0.0001452266,0.0001401377,0.00004524569,0.0005822408,6.26201e-7,0.2717766,0.0001270187,0.001108183,0.5462667],"study_design_scores_gemma":[0.0009201616,0.00007785179,0.5976067,0.00009091878,0.00004574369,0.0001707465,0.0002211051,0.000008869937,0.2088813,0.00006824957,0.1915676,0.0003408183],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964661,0.0003589816,0.0002552545,0.0008220729,0.0005715616,0.0005924854,0.000006493554,0.0001473913,0.0007796683],"genre_scores_gemma":[0.9834468,0.00007489302,0.01329459,0.0003081633,0.0005907767,0.0001209121,0.0001189185,0.00003926445,0.002005643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5459259,"threshold_uncertainty_score":0.9999836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02453958288751804,"score_gpt":0.2619083479543028,"score_spread":0.2373687650667848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}