{"id":"W2055725555","doi":"10.1016/j.neuroscience.2011.08.015","title":"Brn-3b inhibits generation of amacrine cells by binding to and negatively regulating DLX1/2 in developing retina","year":2011,"lang":"en","type":"article","venue":"Neuroscience","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Japan Society for the Promotion of Science; Sumitomo Foundation; Takeda Science Foundation","keywords":"Biology; Homeobox; Ectopic expression; Transcription factor; Retina; Cell biology; Cell fate determination; Amacrine cell; Basic helix-loop-helix; Neuroscience; Genetics; Gene; DNA-binding protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001462837,0.0000798995,0.00007298964,0.0000583525,0.00005611007,0.00001345035,0.00009746029,0.00003311304,0.000001633256],"category_scores_gemma":[0.0001246134,0.00007966018,0.00001011104,0.0002355892,0.00006559573,0.000009889522,0.0001079102,0.00003245115,7.667123e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006123964,"about_ca_system_score_gemma":0.00003617254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002107885,"about_ca_topic_score_gemma":0.00001976236,"domain_scores_codex":[0.999267,0.0000272326,0.0001637988,0.0002907112,0.00009690061,0.0001542971],"domain_scores_gemma":[0.9997824,0.000004707104,0.00006345836,0.00007627572,0.00003136436,0.00004177233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001272163,0.000008708069,0.01425909,0.000007212864,3.021398e-7,5.575183e-7,0.0002000503,0.000007369903,0.9843047,0.00004996988,0.0001576556,0.0009916897],"study_design_scores_gemma":[0.0001261956,0.0000990976,0.04404199,0.00001912862,7.569724e-7,0.000002123586,0.00003668641,0.0001334175,0.9547318,0.0000127675,0.0006967574,0.00009934543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979362,0.00003125678,0.001246623,0.00008880329,0.00007938821,0.0001104874,0.000002123223,0.000003724735,0.0005013653],"genre_scores_gemma":[0.9952519,0.00007149229,0.004216742,0.0002491327,0.00001039142,0.000005089375,0.000004589723,0.000006114734,0.0001845299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0297829,"threshold_uncertainty_score":0.3248448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04104874215664219,"score_gpt":0.2526198449182633,"score_spread":0.2115711027616211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}