{"id":"W2055734284","doi":"10.1053/j.gastro.2014.01.022","title":"Risk of Colorectal Cancer for Carriers of Mutations in MUTYH, With and Without a Family History of Cancer","year":2014,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":230,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Cancer Care Ontario","funders":"Cancer Council Victoria; National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health","keywords":"MUTYH; Medicine; Colorectal cancer; Oncology; Cancer; Family history; Internal medicine; Population; Mutation; Genetics; Germline mutation; Gene; Biology; Environmental health","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000284633,0.000528599,0.0005479236,0.001141032,0.0007183303,0.0005288676,0.0004089789,0.001018811,0.006451033],"category_scores_gemma":[0.00209228,0.0003808077,0.0009539597,0.0008667809,0.000426008,0.0005516625,0.0004517612,0.0007696064,0.0004679595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000185589,"about_ca_system_score_gemma":0.0002705274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00540057,"about_ca_topic_score_gemma":0.003983825,"domain_scores_codex":[0.9997442,0.00005973452,0.0000170872,0.00007166439,0.00003254527,0.00007475678],"domain_scores_gemma":[0.9990823,0.0002713899,0.0002571873,0.00005242707,0.00004297966,0.0002937561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001924988,0.0001322941,0.9921496,0.00001931085,0.0002113717,0.001566755,0.0001341866,0.000111741,0.001589135,0.00009323884,0.0002089906,0.001858313],"study_design_scores_gemma":[0.00004550651,0.0005835858,0.9939954,0.000008256308,0.0002002743,0.003614019,0.0003768108,0.000612595,0.0001296815,0.000153679,0.0002618748,0.00001830525],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985082,0.0002842993,0.00009601256,0.00007671554,0.00002094777,0.000004937152,0.0001937446,0.0000090493,0.000806237],"genre_scores_gemma":[0.9989606,0.00008640567,0.0000694542,0.00002386835,0.00002593251,0.000004137576,0.0001755753,0.000004056963,0.0006498776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006451033,"threshold_uncertainty_score":0.02158087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01129099958412675,"score_gpt":0.264858894412517,"score_spread":0.2535678948283903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}