{"id":"W2055735604","doi":"10.1002/eji.201444826","title":"Application of central immunologic concepts to cancer: Helping T cells and B cells become intolerant of tumors","year":2014,"lang":"en","type":"letter","venue":"European Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Alberta Innovates","keywords":"Biology; Immunology; Epitope; Antigen; Immune system; T cell; CD8; Immune tolerance; Cytotoxic T cell; Immunity; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001282608,0.0006932694,0.0007663242,0.0002817798,0.0009681936,0.001669866,0.0009911484,0.01275929,0.002485708],"category_scores_gemma":[0.005753276,0.0003804646,0.0005593883,0.0002275871,0.002494589,0.001514706,0.0005866161,0.01150077,0.002663909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00152204,"about_ca_system_score_gemma":0.0009031649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003506311,"about_ca_topic_score_gemma":0.0004388826,"domain_scores_codex":[0.9988136,0.000409371,0.0001093223,0.0001912859,0.0003599907,0.0001164901],"domain_scores_gemma":[0.9971697,0.001613433,0.0002120685,0.0001659343,0.0005018999,0.0003370586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003434798,0.0001410143,0.0009474208,0.0006256393,0.00004265531,0.007628213,0.0002550763,0.000218373,0.005399778,0.009649335,0.8973215,0.07742745],"study_design_scores_gemma":[0.0001781987,0.000293744,0.001143213,0.0001512504,0.00003171524,0.01535266,0.0001742868,0.0005289954,0.002891941,0.01317644,0.9660423,0.00003529484],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003360681,0.02076124,0.001255024,0.882533,0.08632318,0.00003306703,0.00004957439,0.0001468956,0.005537339],"genre_scores_gemma":[0.05138491,0.029975,0.001655745,0.7414191,0.1595244,0.0001044808,0.0000568451,0.00005022662,0.01582932],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01275929,"threshold_uncertainty_score":0.01104319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01097197004143986,"score_gpt":0.238090941359726,"score_spread":0.2271189713182862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}