{"id":"W2055758111","doi":"10.3892/etm.2014.1965","title":"Conditional and inducible transgene expression in endothelial and hematopoietic cells using Cre/loxP and tetracycline-off systems","year":2014,"lang":"en","type":"article","venue":"Experimental and Therapeutic Medicine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"Heart and Stroke Foundation of Canada","keywords":"Transactivation; Cre recombinase; Biology; Transgene; Molecular biology; Reporter gene; Tetracycline; Green fluorescent protein; Gene expression; TetR; Gene; Genetically modified mouse; Repressor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002966095,0.0001668988,0.0002198153,0.0000682824,0.00009486432,0.00001911383,0.00004974711,0.00009965339,0.00004186978],"category_scores_gemma":[0.000006115957,0.0001297323,0.00001294101,0.00004134564,0.0002931464,0.000006158125,0.00004448625,0.00009206255,4.919015e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008198443,"about_ca_system_score_gemma":0.00001620332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002955941,"about_ca_topic_score_gemma":0.000004426421,"domain_scores_codex":[0.9989799,0.0001256279,0.0001997482,0.0003467496,0.0001554932,0.0001924942],"domain_scores_gemma":[0.9996498,0.0000359754,0.00004086429,0.0001275979,0.00001516054,0.000130563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004231691,0.00005187031,0.0008062503,0.00004109983,0.00002079859,0.000002614476,0.0005394192,0.000005716077,0.9968431,0.00006852038,0.000009409608,0.00118805],"study_design_scores_gemma":[0.003251564,0.001806249,0.0004593061,0.00008302387,0.00001102314,0.00009181521,0.0007214652,0.001145976,0.9908207,0.0001337234,0.001316161,0.0001590115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9581733,0.04105794,0.0002552094,0.0001112284,0.00006421581,0.0002421247,0.000008939845,0.00000465013,0.00008233666],"genre_scores_gemma":[0.9981743,0.001166346,0.00007627809,0.0002431192,0.0002043412,0.00002063733,0.00002196581,0.0000189351,0.00007414968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04000087,"threshold_uncertainty_score":0.5290331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02916469943458003,"score_gpt":0.3228604475155342,"score_spread":0.2936957480809541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}