{"id":"W2055758111","doi":"10.3892/etm.2014.1965","title":"Conditional and inducible transgene expression in endothelial and hematopoietic cells using Cre/loxP and tetracycline-off systems","year":2014,"lang":"en","type":"article","venue":"Experimental and Therapeutic Medicine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"Heart and Stroke Foundation of Canada","keywords":"Transactivation; Cre recombinase; Biology; Transgene; Molecular biology; Reporter gene; Tetracycline; Green fluorescent protein; Gene expression; TetR; Gene; Genetically modified mouse; Repressor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006259704,0.0005128314,0.0004792705,0.0005832301,0.0002486013,0.0005644119,0.0006580242,0.0006393962,0.00197531],"category_scores_gemma":[0.000322764,0.0003566485,0.0004081871,0.0003033049,0.0004422859,0.0006207574,0.0005280285,0.001358501,0.0008383272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000218329,"about_ca_system_score_gemma":0.0003715212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003262472,"about_ca_topic_score_gemma":0.0005898255,"domain_scores_codex":[0.9994672,0.00007361123,0.00005993266,0.0001377236,0.0001766313,0.0000850143],"domain_scores_gemma":[0.9996898,0.00004926916,0.00009454388,0.00005898574,0.0000435217,0.00006397476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004898465,0.00003114562,0.00009357344,0.00007714021,0.00000598324,0.00009023456,0.00002183449,0.00003067305,0.9969111,0.0004667379,0.00008023646,0.002142508],"study_design_scores_gemma":[0.00004519403,0.0003924047,0.001696714,0.00002956489,0.00006032261,0.001332926,0.00004118226,0.0009029557,0.9759325,0.0001586923,0.01939101,0.00001657502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6786779,0.009264906,0.2976034,0.0004341974,0.0005739523,0.0009416871,0.002202673,0.001292027,0.009009419],"genre_scores_gemma":[0.814092,0.009611458,0.1422436,0.0004299651,0.0001686763,0.001332298,0.00520936,0.000521632,0.02639106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00197531,"threshold_uncertainty_score":0.006608009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02916469943458003,"score_gpt":0.3228604475155342,"score_spread":0.2936957480809541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}