{"id":"W2055847083","doi":"10.1016/j.bpj.2008.09.045","title":"Effects on Conformational States of the Rabbit Sodium/Glucose Cotransporter through Modulation of Polarity and Charge at Glutamine 457","year":2009,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Cotransporter; Biophysics; Sugar; Sodium; Biochemistry; Stereochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006246957,0.00008790835,0.0001190276,0.00001531141,0.000073221,0.000005750424,0.00006485906,0.0000721203,0.000009151599],"category_scores_gemma":[0.000004661207,0.00005935704,0.00009845669,0.00004323536,0.00006430922,0.00001163465,0.000007543462,0.00007329038,7.884101e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008565852,"about_ca_system_score_gemma":0.00001605741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000221714,"about_ca_topic_score_gemma":7.453247e-7,"domain_scores_codex":[0.9994022,0.00002364235,0.0002088526,0.00008552244,0.0001846196,0.0000951254],"domain_scores_gemma":[0.9996414,0.000008202118,0.0001570935,0.00007828802,0.00008026905,0.00003478148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002387612,0.00009182596,0.001627278,0.00002276987,0.00002037733,4.797446e-7,0.0001028609,0.0000599212,0.9965217,0.0004099713,0.00003059797,0.0008735194],"study_design_scores_gemma":[0.0005011504,0.0002271478,0.3321026,0.00001883176,0.00001279861,0.000004301597,0.000004037118,0.0002834639,0.6663654,0.0002761739,0.0001581812,0.00004588404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998692,0.00004680932,0.0007369798,0.0002817106,0.0000677545,0.00009335815,0.0000283032,0.000001970522,0.00005116516],"genre_scores_gemma":[0.9994274,0.00007141245,0.0000476102,0.00014015,0.0001807589,6.722806e-7,0.00009003369,0.000004181963,0.00003780341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3304753,"threshold_uncertainty_score":0.242051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00549884464208637,"score_gpt":0.2146130946351168,"score_spread":0.2091142499930304,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}