{"id":"W2055851996","doi":"10.1111/j.1365-2036.2012.05214.x","title":"Long‐term outcome of a third anti‐<scp>TNF</scp> monoclonal antibody after the failure of two prior anti‐<scp>TNF</scp>s in inflammatory bowel disease","year":2012,"lang":"en","type":"article","venue":"Alimentary Pharmacology & Therapeutics","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Ulcerative colitis; Inflammatory bowel disease; Tumor necrosis factor alpha; Internal medicine; Hazard ratio; Gastroenterology; Disease; Infliximab; Colitis; TNF inhibitor; Immunology; Confidence interval","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001661921,0.0002193427,0.0004440725,0.0003784205,0.0006088989,0.00067549,0.0003170215,0.0006118676,0.000788731],"category_scores_gemma":[0.004009669,0.0001567605,0.0008342842,0.0003351631,0.0004004841,0.0004333513,0.000414184,0.0007611763,0.0002175366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005251962,"about_ca_system_score_gemma":0.0003339804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001247725,"about_ca_topic_score_gemma":0.00150437,"domain_scores_codex":[0.9992906,0.0002120442,0.00008197627,0.00006953389,0.0001378493,0.0002080653],"domain_scores_gemma":[0.9936389,0.00132547,0.003015131,0.0002661967,0.0003701791,0.001384043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002395502,0.0002413391,0.9900442,0.00002029869,0.0002106202,0.0006009231,0.00008387015,0.0001739103,0.0004046153,0.00002146481,0.0001140014,0.005689128],"study_design_scores_gemma":[0.00007391145,0.003225631,0.9940526,0.00002278902,0.0001744766,0.001489509,0.0001169182,0.0003553919,0.0001974313,0.00003988791,0.0002406283,0.0000107826],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988379,0.0007996705,0.00004936035,0.00004669895,0.000007978369,0.000003915287,0.00005652822,0.000001828544,0.0001961722],"genre_scores_gemma":[0.9996265,0.0001082268,0.00001293469,0.00002788856,0.00001496056,0.00000290624,0.0001349465,7.059841e-7,0.000070794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001661921,"threshold_uncertainty_score":0.008789241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01359716434251156,"score_gpt":0.3082492880873252,"score_spread":0.2946521237448136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}