{"id":"W2055884944","doi":"10.1182/blood-2013-12-540971","title":"Phase 2 trial of CPX-351, a fixed 5:1 molar ratio of cytarabine/daunorubicin, vs cytarabine/daunorubicin in older adults with untreated AML","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":336,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Celator Pharmaceuticals","keywords":"Daunorubicin; Cytarabine; Medicine; Internal medicine; Leukemia; Oncology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009577667,0.0005052909,0.001529845,0.0007359299,0.00006023442,0.00001729164,0.0003903792,0.0003399307,0.0003240336],"category_scores_gemma":[0.0008751726,0.0003922009,0.000213194,0.001327402,0.0003340755,0.0001795989,0.0001089218,0.0006907537,0.00003701594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001604776,"about_ca_system_score_gemma":0.0007479514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001602901,"about_ca_topic_score_gemma":0.0002962342,"domain_scores_codex":[0.995753,0.0003980462,0.00126233,0.0007557084,0.001051444,0.0007793996],"domain_scores_gemma":[0.9970293,0.0004016994,0.0004665153,0.001159635,0.0006102259,0.0003326374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5137882,0.03905704,0.03701603,0.002296429,0.001571664,0.0008839256,0.005277124,0.0001782032,0.3881347,0.0004076464,0.003517537,0.007871539],"study_design_scores_gemma":[0.6331099,0.0188203,0.009557768,0.001212649,0.0006170558,0.0001152041,0.000330019,0.003215512,0.3321724,0.00002246691,0.0003777319,0.0004490896],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941513,0.0002021686,0.0003339314,0.0006418453,0.00007716498,0.003051094,0.0000704308,0.00008437615,0.0013877],"genre_scores_gemma":[0.9969743,0.00009943559,0.001292958,0.0001844252,0.000282208,0.0001631753,0.0002534852,0.0001011514,0.000648797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1193217,"threshold_uncertainty_score":0.999853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008712615199877411,"score_gpt":0.268214824499536,"score_spread":0.2595022092996586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}