{"id":"W2055934782","doi":"10.1016/j.vaccine.2010.01.040","title":"Modified binding assay for improved sensitivity and specificity in the detection of residual pertussis toxin in vaccine preparations","year":2010,"lang":"en","type":"article","venue":"Vaccine","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Canada","funders":"","keywords":"Pertussis toxin; Polyclonal antibodies; Monoclonal antibody; Toxoid; Pertussis vaccine; Toxin; Diphtheria toxin; Antibody; In vivo; Microbiology; Chemistry; Virology; Biology; Immunology; Immunization; G protein; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001787043,0.001768954,0.001371807,0.001262858,0.0005998411,0.0008190181,0.002477059,0.002950564,0.003840894],"category_scores_gemma":[0.002443136,0.001269681,0.0009056316,0.0006567342,0.0006540181,0.0005879867,0.0009900762,0.003629632,0.003119116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007852352,"about_ca_system_score_gemma":0.0005945408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001791501,"about_ca_topic_score_gemma":0.002391734,"domain_scores_codex":[0.9965279,0.00138838,0.0001903627,0.0006322139,0.0009424525,0.0003188657],"domain_scores_gemma":[0.998066,0.0008129348,0.000137884,0.0003461179,0.000455901,0.0001810652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001239784,0.00007176063,0.0001030714,0.00004664604,0.0000147967,0.00001653269,0.00002397981,0.00008256078,0.9970612,0.0001212767,0.0001200065,0.002214151],"study_design_scores_gemma":[0.00002508942,0.0005809333,0.001449328,0.00001679639,0.00005532429,0.0004027891,0.00001521012,0.005922313,0.9885516,0.0001128856,0.00282756,0.0000400903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4106074,0.003951042,0.5757692,0.0006738036,0.0004502686,0.0006353318,0.0007171302,0.002837511,0.004358328],"genre_scores_gemma":[0.6530485,0.001662245,0.3256553,0.001023805,0.0001448082,0.0007030211,0.002823747,0.0003058569,0.01463276],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003840894,"threshold_uncertainty_score":0.01284909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01649805917309217,"score_gpt":0.2581087167396546,"score_spread":0.2416106575665624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}