{"id":"W2055936473","doi":"10.1134/s0026893310010127","title":"Silencing of the CCNB1, Her2, and PKC genes by small interfering RNA differently retards the division of different human cancer cell lines","year":2010,"lang":"en","type":"article","venue":"Molecular Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Beef Cattle Research Council","keywords":"Gene silencing; Cell cycle; Biology; Small interfering RNA; Cell biology; Cancer cell; Transfection; Cell growth; RNA interference; Cell division; Cell; Cell culture; Gene; Cancer research; Molecular biology; Cancer; Genetics; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001319394,0.0002242068,0.0001836066,0.0001781532,0.0001152487,0.0002332174,0.0001036469,0.0001214916,0.0009917099],"category_scores_gemma":[0.0001204768,0.0000835938,0.0001278775,0.0001373668,0.0001492357,0.0001111783,0.00008480708,0.0002738021,0.0002514115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002772625,"about_ca_system_score_gemma":0.0002251296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006559507,"about_ca_topic_score_gemma":0.001191133,"domain_scores_codex":[0.9999028,0.00001292157,0.00001101879,0.00002899854,0.00002839638,0.00001588586],"domain_scores_gemma":[0.9999286,0.00002125639,0.00001643864,0.00001277099,0.000008707862,0.00001222677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003968035,0.000008594393,0.0001010262,0.00001305971,0.000001871069,0.00001119425,0.000006911224,0.00002866957,0.9990178,0.00005722838,0.00001620594,0.0006976958],"study_design_scores_gemma":[0.000007205502,0.00007270577,0.001522312,0.000001803719,0.000006922693,0.0000589766,0.000007428963,0.0003237958,0.9965596,0.00001702885,0.001421132,0.000001157215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930541,0.001610623,0.002885537,0.00005995496,0.00002364079,0.0000336787,0.0005146509,0.00006417021,0.001753701],"genre_scores_gemma":[0.9912571,0.001079939,0.003686779,0.00003723674,0.000007417013,0.00007171364,0.0009529452,0.00002589347,0.002881019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009917099,"threshold_uncertainty_score":0.003317595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008676423647100069,"score_gpt":0.2714008280986182,"score_spread":0.2627244044515181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}