{"id":"W2055948554","doi":"10.1503/cmaj.110598","title":"The perilous state of independent randomized clinical trials and related applied research in Canada","year":2012,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Meta-analysis and systematic reviews","field":"Decision Sciences","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Hamilton Health Sciences; University of British Columbia","funders":"Canadian Institutes of Health Research; National Institutes of Health; Medical Research Council; National Institute for Health and Care Research","keywords":"Life expectancy; Intensive care medicine; Randomized controlled trial; Medicine; Clinical trial; Gerontology; Environmental health; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.3106217,0.001145533,0.005904969,0.006965823,0.003731382,0.01240664,0.00552624,0.004224333,0.007547424],"category_scores_gemma":[0.5436318,0.001981909,0.003184699,0.01870549,0.01189789,0.003729677,0.004860348,0.006628184,0.0006208751],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.08972292,"about_ca_system_score_gemma":0.3372433,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.805958,"about_ca_topic_score_gemma":0.863717,"domain_scores_codex":[0.6518377,0.2144873,0.04566751,0.02139665,0.0610517,0.005559145],"domain_scores_gemma":[0.2802662,0.520967,0.04182131,0.02893834,0.1190279,0.008979253],"domain_codex":null,"domain_gemma":"incentives","domain_candidate":"incentives","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00577919,0.0002859686,0.05050232,0.09197202,0.01494929,0.0003165058,0.003164232,0.00521727,0.0007560792,0.1181287,0.1343791,0.5745493],"study_design_scores_gemma":[0.01114449,0.001508517,0.1286331,0.1754957,0.01991778,0.0006331474,0.002909804,0.01176585,0.001846422,0.1459346,0.4995045,0.0007061141],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.01020114,0.6381758,0.03205588,0.2785375,0.009706825,0.002907815,0.008706422,0.0003161421,0.01939254],"genre_scores_gemma":[0.3966853,0.3433252,0.09636614,0.140549,0.008230668,0.005371464,0.004329692,0.0005200473,0.00462253],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9102771,"threshold_uncertainty_score":0.8501262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6530825769512333,"score_gpt":0.5648524757498292,"score_spread":0.08823010120140407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}